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The pressure flow study investigation of pathophysiology of post-micturition dribble in male patients

  • Urology - Original Paper
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Abstract

Purpose

In this study, we aimed to elucidate the pathophysiology of post-micturition dribble (PMD) through analyzing several variables including pressure flow study (PFS) findings and symptoms questionnaire.

Methods

We retrospectively analyzed male patients who visited our department between 2010 and 2020. We used modified international prostate symptom score (m-IPSS), which consists of eight sub-score related to lower urinary tract symptoms (Incomplete Emptying, Frequency, Intermittency, Urgency, Weak Stream, Straining, Nocturia, and PMD) and one question related to quality of life (QOL). Multivariate regression analysis was conducted to evaluate the relationship between PMD and the variables, including age, prostate volume (PV), body mass index, bladder outlet obstruction index (BOOI), bladder contractility index, and bladder voiding efficiency, which were obtained by PFS.

Results

A total of 143 male patients were analyzed. The patients with PMD showed significantly larger PV and higher BOOI, and worse IPSS total and QOL score than those without PMD. Multivariate regression analysis showed that large PV and BOOI were significantly associated with PMD. In Spearman’s correlation analysis, PMD and each m-IPSS sub-score except nocturia had significant positive correlation. Furthermore, Spearman’s correlation analysis showed that PMD and QOL had significant strong positive correlation.

Conclusion

PMD was significantly associated with large PV and BOO evaluated by PFS. Furthermore, PMD significantly exacerbated QOL. The severity of PMD and the other m-IPSS sub-score except nocturia could have intercorrelation with each other.

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Funding

This study has not been funded by any groups.

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Authors and Affiliations

  1. Department of Urology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan

    Mamoru Hashimoto, Saizo Fujimoto, Ken Kuwahara, Mitsuhisa Nishimoto, Shogo Adomi, Eri Banno, Takafumi Minami, Kazutoshi Fujita, Kazuhiro Yoshimura & Hirotsugu Uemura

  2. Department of Pelvic Floor Center, Kochi Medical School, Kochi University, Nankoku, Kochi, 783-8505, Japan

    Nobutaka Shimizu

  3. Department of Urology, Nara Hospital Kindai University Faculty of Medicine, Ikoma, Nara, Japan

    Akihide Hirayama

Authors
  1. Mamoru Hashimoto
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  2. Nobutaka Shimizu
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  3. Saizo Fujimoto
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  4. Ken Kuwahara
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  5. Mitsuhisa Nishimoto
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  6. Shogo Adomi
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  7. Eri Banno
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  8. Takafumi Minami
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  9. Kazutoshi Fujita
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  12. Hirotsugu Uemura
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Corresponding author

Correspondence to Nobutaka Shimizu.

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Conflict of interest

All authors declare that they have no financial or non-financial conflict of interest related to this study.

Ethical approval

This study protocol was approved by the Institutional Review Board (IRB) of the Faculty of Medicine in Kindai University (approval number: R02-106). In this retrospective study, IRB admitted that informed consent was waived, and opt-out method was applied to obtain consent on this study.

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Hashimoto, M., Shimizu, N., Fujimoto, S. et al. The pressure flow study investigation of pathophysiology of post-micturition dribble in male patients. Int Urol Nephrol 55, 69–74 (2023). https://doi.org/10.1007/s11255-022-03367-2

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  • DOI: https://doi.org/10.1007/s11255-022-03367-2

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