Abstract
A simple procedure is examined for forming a selective sensor coating using mixed self-assembling thiol monolayers functionalized by molecules of the sulfanilamide antibiotic, sulfamethoxazol (SMX). A model is proposed for the interface processes, which accounts for the complex dependence of the adsorption capacity of the coatings obtained on the surface density of the reactive groups and the low adsorption capacity at high reaction site concentrations. The model was supported by competitive inhibition analysis.
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Translated from Teoreticheskaya i Éksperimental’naya Khimiya, Vol. 44, No. 3, pp. 158–164, May–June, 2008.
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Snopok, B.A., Boltovets, P.N. & Rowell, F.J. Interface functional architecture using mixed thiol monolayers: Effect of the composition and spatial organization on the immobilization of low-molecular-weight ligands. Theor Exp Chem 44, 165–171 (2008). https://doi.org/10.1007/s11237-008-9024-y
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DOI: https://doi.org/10.1007/s11237-008-9024-y