Abstract
Purpose
The aim of this study was to examine the validity of the EuroQOL five dimensions questionnaire (EQ-5D) using a nationally representative data from the National Health Interview Survey (NHIS) through comparison with short-form 36 (SF-36).
Methods
Data for this study came from the 2009 NHIS in Taiwan. The study sample was the 4007 participants aged 20–64 years who completed the survey. We used SUDAAN 10.0 (SAS-Callable) to carry out weighed estimation and statistical inference. The EQ index was estimated using norm values from a Taiwanese study as well as from Japan and the United Kingdom (UK). The SF-36 score was standardized using American norm values.
Results
In terms of concurrent validity, the EQ-5D met the five hypotheses. The results did not fulfill hypothesis that women would have lower visual analogue scale (EQ-VAS) scores. In terms of discriminant validity, the EQ-5D fulfilled two hypotheses. Our results approached but did not fulfill hypothesis that there would be a weak association between the physical and psychological dimensions of the EQ-5D and the mental component summary score of the SF-36. Results were comparable regardless of whether the Japanese or UK norm value sets were used.
Conclusions
We were able to fulfill many, not all of our validity hypotheses regardless of whether the established Japanese or UK norm value sets or the Taiwanese norm values were used. The EQ-5D is an effective and simple instrument for assessing health-related quality of life of general population in Taiwan.
References
Jia, H., & Lubetkin, E. I. (2005). The impact of obesity on health-related quality-of-life in the general adult US population. J Public Health (Oxf), 27(2), 156–164.
Coons, S. J., Rao, S., Keininger, D. L., & Hays, R. D. (2000). A comparative review of generic quality-of-life instruments. Pharmacoeconomics, 17(1), 13–35.
Ware, J. E., Snow, K. K., Kosinski, M., Gandek, B., & New England Medical Center Hospital Health Institute. (1993). SF-36 health survey: manual and interpretation guide. The Health Institute, New England Medical Center.
Ware, J. E, Jr, & Gandek, B. (1998). Overview of the SF-36 Health Survey and the International Quality of Life Assessment (IQOLA) Project. Journal of Clinical Epidemiology, 51(11), 903–912.
Lu, J. F., Tseng, H. M., & Tsai, Y. J. (2003). Assessment of health-related quality of life in Taiwan (I): Development and psychometric testing of SF-36 Taiwan version. Taiwan Journal of Public Health, 22(6), 501–511.
Tseng, H. M., Lu, J. F., & Tsai, Y. J. (2003). Assessment of health-related quality of life in Taiwan (II): Norming and validation of SF-36 Taiwan version. Taiwan Journal of Public Health, 22(6), 512–518.
Glasziou, P., Alexander, J., Beller, E., Clarke, P., & Group, A. C. (2007). Which health-related quality of life score? A comparison of alternative utility measures in patients with Type 2 diabetes in the ADVANCE trial. Health and Quality of Life Outcomes, 5, 21. doi:10.1186/1477-7525-5-21.
Mahadeva, S., Wee, H. L., Goh, K. L., & Thumboo, J. (2009). The EQ-5D (Euroqol) is a valid generic instrument for measuring quality of life in patients with dyspepsia. BMC Gastroenterology, 9, 20. doi:10.1186/1471-230X-9-20.
Schrag, A., Selai, C., Jahanshahi, M., & Quinn, N. P. (2000). The EQ-5D—A generic quality of life measure-is a useful instrument to measure quality of life in patients with Parkinson’s disease. Journal of Neurology, Neurosurgery and Psychiatry, 69(1), 67–73.
Wang, H. M., Beyer, M., Gensichen, J., & Gerlach, F. M. (2008). Health-related quality of life among general practice patients with differing chronic diseases in Germany: Cross sectional survey. BMC Public Health, 8, 246. doi:10.1186/1471-2458-8-246.
Liou, H. H., Chiang, S. S., Wu, S. C., Yang, W. C., & Huang, T. P. (1994). Intravenous infusion or nebulization of salbutamol for treatment of hyperkalemia in patients with chronic renal failure. Zhonghua Yi Xue Za Zhi (Taipei), 53(5), 276–281.
Lang, H. C., Chuang, L., Shun, S. C., Hsieh, C. L., & Lan, C. F. (2010). Validation of EQ-5D in patients with cervical cancer in Taiwan. Supportive Care in Cancer, 18(10), 1279–1286. doi:10.1007/s00520-009-0745-9.
Chang, T. J., Tarn, Y. H., Hsieh, C. L., Liou, W. S., Shaw, J. W., & Chiou, X. G. (2007). Taiwanese version of the EQ-5D: validation in a representative sample of the Taiwanese population. Journal of the Formosan Medical Association, 106(12), 1023–1031. doi:10.1016/S0929-6646(08)60078-9.
Tsuchiya, A., Ikeda, S., Ikegami, N., Nishimura, S., Sakai, I., Fukuda, T., et al. (2002). Estimating an EQ-5D population value set: The case of Japan. Health Economics, 11(4), 341–353. doi:10.1002/hec.673.
Lee, H. Y., Hung, M. C., Hu, F. C., Chang, Y. Y., Hsieh, C. L., & Wang, J. D. (2013). Estimating quality weights for EQ-5D (EuroQol-5 dimensions) health states with the time trade-off method in Taiwan. Journal of the Formosan Medical Association,. doi:10.1016/j.jfma.2012.12.015.
Dolan, P. (1997). Modeling valuations for EuroQol health states. Medical Care, 35(11), 1095–1108.
Szende, A., Oppe, M., Devlin, N. J., & EuroQol-Group. (2007). EQ-5D value sets: Inventory, comparative review and user guide: Inventory, comparative review and user guide. Berlin: Springer.
Kontodimopoulos, N., Pappa, E., Niakas, D., Yfantopoulos, J., Dimitrakaki, C., & Tountas, Y. (2008). Validity of the EuroQoL (EQ-5D) instrument in a Greek general population. Value Health, 11(7), 1162–1169. doi:10.1111/j.1524-4733.2008.00356.x.
Shafie, A. A., Hassali, M. A., & Liau, S. Y. (2011). A cross-sectional validation study of EQ-5D among the Malaysian adult population. Quality of Life Research, 20(4), 593–600. doi:10.1007/s11136-010-9774-6.
Savoia, E., Fantini, M. P., Pandolfi, P. P., Dallolio, L., & Collina, N. (2006). Assessing the construct validity of the Italian version of the EQ-5D: Preliminary results from a cross-sectional study in North Italy. Health and Quality of Life Outcomes, 4, 47. doi:10.1186/1477-7525-4-47.
Ware, J. E, Jr, Gandek, B., Kosinski, M., Aaronson, N. K., Apolone, G., Brazier, J., et al. (1998). The equivalence of SF-36 summary health scores estimated using standard and country-specific algorithms in 10 countries: Results from the IQOLA Project. International Quality of Life Assessment. Journal of Clinical Epidemiology, 51(11), 1167–1170.
Yu, S. T., Chang, H. Y., Lin, M. C., & Lin, Y. H. (2009). Agreement between self-reported and health insurance claims on utilization of health care: A population study. Journal of Clinical Epidemiology, 62(12), 1316–1322. doi:10.1016/j.jclinepi.2009.01.016.
Myers, C., & Wilks, D. (1999). Comparison of Euroqol EQ-5D and SF-36 in patients with chronic fatigue syndrome. Quality of Life Research, 8(1–2), 9–16.
Brazier, J., Jones, N., & Kind, P. (1993). Testing the validity of the Euroqol and comparing it with the SF-36 health survey questionnaire. Quality of Life Research, 2(3), 169–180.
Aburuz, S., Bulatova, N., Twalbeh, M., & Gazawi, M. (2009). The validity and reliability of the Arabic version of the EQ-5D: A study from Jordan. Annals of Saudi Medicine, 29(4), 304–308.
Cleemput, I., Kesteloot, K., Moons, P., Vanrenterghem, Y., Van Hooff, J. P., Squifflet, J. P., et al. (2004). The construct and concurrent validity of the EQ-5D in a renal transplant population. Value Health, 7(4), 499–509. doi:10.1111/j.1524-4733.2004.74013.x.
Badia Llach, X., Herdman, M., & Schiaffino, A. (1999). Determining correspondence between scores on the EQ-5D “thermometer” and a 5-point categorical rating scale. Medical Care, 37(7), 671–677.
Kind, P., Dolan, P., Gudex, C., & Williams, A. (1998). Variations in population health status: rEsults from a United Kingdom national questionnaire survey. BMJ, 316(7133), 736–741.
Luo, N., Chew, L. H., Fong, K. Y., Koh, D. R., Ng, S. C., Yoon, K. H., et al. (2003). Validity and reliability of the EQ-5D self-report questionnaire in Chinese-speaking patients with rheumatic diseases in Singapore. Annals of the Academy of Medicine, Singapore, 32(5), 685–690.
Lubetkin, E. I., Jia, H., & Gold, M. R. (2004). Construct validity of the EQ-5D in low-income Chinese American primary care patients. Quality of Life Research, 13(8), 1459–1468.
Brazier, J., Connell, J., Papaioannou, D., Mukuria, C., Mulhern, B., Peasgood, T., et al. (2014). A systematic review, psychometric analysis and qualitative assessment of generic preference-based measures of health in mental health populations and the estimation of mapping functions from widely used specific measures. Health Technology Assessment, 18(34), 1–188. doi:10.3310/hta18340.
Acknowledgments
This study was supported by the National Health Research Institute, Taiwan, through Grants 01A1-PHPP18-014, 02A1-PHPP17-014. This study is based on data from the National Health Interview Survey. Original Database provided by Health Promotion Administration, Ministry of Health and Welfare, Taiwan, and Food and Drug Administration, Ministry of Health and Welfare, Taiwan, and National Health Research Institute, Taiwan. We are grateful for the NHIS team members, especially for the ‘Fieldwork Operation Center of Community-based Health Survey.’ The interpretation and conclusions contained herein do not represent those of Promotion Administration, Ministry of Health and Welfare, Taiwan, and Food and Drug Administration, Ministry of Health and Welfare, Taiwan.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Yu, ST., Chang, HY., Yao, KP. et al. Validity of EQ-5D in general population of Taiwan: results of the 2009 National Health Interview and Drug Abuse Survey of Taiwan. Qual Life Res 24, 2541–2548 (2015). https://doi.org/10.1007/s11136-015-0978-7
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11136-015-0978-7