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Essential oils of Lavandula genus: a systematic review of their chemistry

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Abstract

Lavandula species are one of the most useful aromatic and medicinal plants with a great economic value for pharmaceutical, food and flavor industries, cosmetics, perfumery, and aromatherapy. The pleasant fragrance, physiological effects, and commercial significance are due to the their essential oils, with a highly variable composition dependent on the genetic, environmental and processing factors. This paper provides a systematic view on the chemistry of lavender essential oils especially considering the studies in the last 15 years. The review presents the characteristic chemical constituents and chemotypes of seventeen Lavandula species. The intra- and interspecific variability is primarily discussed dependent on the geographic area, onto-and morphogenetic factors, and extraction methods. In addition, biosynthesis of lavender terpenes is presented.

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References

  • Aburjai T, Hudaib M, Cavrini V (2005) Chemical composition of the essential oil from different aerial parts of lavender (Lavandula coronopofolia Poiert) (Lamiaceae) grown in Jordan. J Esssent Oil Res 17:49–51

    Article  Google Scholar 

  • Adaszynska-Skwirzynska M, Swarcewicz M, Dobrowolska A (2014) The potential of use lavender from vegetable waste as effective antibacterial and sedative agents. Med Chem 4:734–737

    Google Scholar 

  • Alatrache A, Jamoussi B, Tarhouni R et al (2007) Analysis of the essential oil of Lavandula latifolia from Tunisia. J Essent Oil Bear Pl 10:446–452

    Article  CAS  Google Scholar 

  • Al-Badani RN, Da Silva JK, Setzer WN et al (2016) Variations in essential compositions of Lavandula pubescens (Lamiaceae) aerial parts growing wild in Yemen. Chem Biodivers. doi:10.1002/cbdv.201600286

    Google Scholar 

  • Al-Sarar AS (2014) Chemical composition and larvicidal activity of essential oils isolated from three Saudi medicinal plant species. Bothalia 44:170–178

    Google Scholar 

  • Andoğan BC, Baydar H, Kaya S et al (2002) Antimicrobial activity and chemical composition of some essential oils. Arch Pharm Res 25:860–864

    Article  Google Scholar 

  • Angioni A, Barra A, Coroneo V et al (2006) Chemical composition, seasonal variability, and antifungal activity of Lavandula stoechas L. ssp. stoechas essential oils from stem/leaves and flowers. J Agric Food Chem 54:4364–4370

    Article  CAS  PubMed  Google Scholar 

  • Aprotosoaie AC, Hăncianu M, Costache I-I, Miron A (2014) Linalool: a review on a key odorant molecule with valuable biological properties. Flavour Fragr J 29:193–219

    Article  CAS  Google Scholar 

  • Argentieri MP, De Lucia B, Cristiano G, Pinarosa Avatoa (2016) Compositional analysis of Lavandula pinnata essential oils. Nat Prod Commun 11:287–290

    PubMed  Google Scholar 

  • Aumeeruddy-Elalfi Z, Gurib-Fakim A, Fawzi Mahomoodallya M (2016) Chemical composition, antimicrobial and antibiotic potentiating activity of essential oils from 10 tropical medicinal plants from Mauritius. J Herb Med 6:88–95

    Article  Google Scholar 

  • Bajalan I, Pirbalouti AG (2015) Variation in chemical composition of essential oil of populations of Lavandula × intermedia collected from Western Iran. Ind Crop Prod 69:344–347

    Article  CAS  Google Scholar 

  • Barrazandeh MM (2002) Essential oil composition of Lavandula latifolia Medik from Iran. J Essent Oil Res 14:103–104

    Article  Google Scholar 

  • Barrero AF, Herrador MM, Arteaga P et al (2008) Cultivars of Lavandula lanata Boiss., a good source of lavandulol. Nat Prod Commun 3:379–381

    CAS  Google Scholar 

  • Baydar H (2009) Lavender. Medicinal and aromatic plant. Science and Technology (3th press), vol 51. Suleyman Demirel University Press, Isparta, pp 274–278

    Google Scholar 

  • Belhadj Mostefa M, Kabouche A, Abaza I et al (2014) Chemotypes investigation of Lavandula essential oils growing at different North African soils. J Mater Environ Sci 5:1896–1901

    Google Scholar 

  • Benabdelkader T (2012) Biodiversité, bioactivité et biosynthèse des composes terpéniques volatils des Lavandes Aileés, L. stoechas sensu Lato, un complex d’Espèces Médeterraneés d’Intèrêt Pharmacologique. Dissertation, L’Ecole Normale Supérieure de Komba-Alger (Algérie) et de l”Université Jean-Monnet de Saint-Etienne (France)

  • Benabdelkader T, Zitouni A, Guitton Y et al (2011) Essential oils from wild populations of Algerian Lavandula stoechas L.: composition, chemical variability, and in vitro biological properties. Chem Biodivers 8:937–953

    Article  CAS  PubMed  Google Scholar 

  • Benbelaid F, Bendahou M, Khadir A et al (2012) Antimicrobial activity of essential oil of Lavandula multifida L. J Microbiol Biotechnol Res 2:244–247

    Google Scholar 

  • Bhowal M, Gopal M (2015) Eucalyptol: safety and pharmacological profile. J Pharm Sci 5:125–131

    Google Scholar 

  • Binello A, Orio L, Pignata G et al (2014) Effect of microwaves on the in situ hydrodistillation of four different Lamiaceae. CR Chim 17:181–186

    Article  CAS  Google Scholar 

  • Boeckelmann A (2008) Monoterpene production and regulation in lavenders (Lavandula angustifolia and L. × intermedia). Dissertation, University of British Columbia

  • Bousmaha L, Bekkara FA, Tomi F et al (2005) Advances in the chemical composition of Lavandula dentata L. essential oil from Algeria. J Essent Oil Res 17:292–295

    Article  CAS  Google Scholar 

  • Bousmaha L, Brice Boti J, Bekkara FA et al (2006) Infraspecific chemical variability of the essential oil of Lavandula dentata L. from Algeria. Flavour Fragr J 21:368–372

    Article  CAS  Google Scholar 

  • Bouzouita N, Kachouri F, Hamdi M, Chaabouni MM et al (2005) Volatile constituents and antimicrobial activity of Lavandula stoechas L. oil from Tunisia. J Essent Oil Res 17:584–586

    Article  CAS  Google Scholar 

  • Călinescu I, Gavrila AI, Ivopol M et al (2014) Microwave assisted extraction of essential oils from enzymatically pretreated lavender (Lavandula angustifolia Miller). Cent Eur J Chem 12:829–836

    Article  CAS  Google Scholar 

  • Carrasco A, Tomas V, Tudela J et al (2015a) Comparative study of GC-MS characterization, antioxidant activity and hyaluronidase inhibition of different species of Lavandula and Thymus essential oils. Flavour Fragr J 31:57–69

    Article  CAS  Google Scholar 

  • Carrasco A, Ortiz-Ruiz V, Martinez-Gutierrez R et al (2015b) Lavandula stoechas essential oil from Spain: aromatic profile determined by gas-chromatography-mass spectrometry, antioxidant and lipoxygenase inhibitory bioactivities. Ind Crop Prod 73:16–27

    Article  CAS  Google Scholar 

  • Carrasco A, Martinez-Gutierrez R, Tomas V, Tudela J (2016) Lavandin (Lavandula × intermedia Emeric ex Loiseleur) essential oil from Spain: determination of aromatic profile by gas chromatography-mass spectrometry, antioxidant and lipoxygenase inhibitory bioactivities. Nat Prod Res 30:1123–1130

    Article  CAS  PubMed  Google Scholar 

  • Cassel E, Vargas RFM, Martinez N, Lorenzo D et al (2009) Steam distillation modeling for essential oil extraction process. Ind Crop Prod 29:171–176

    Article  CAS  Google Scholar 

  • Cerpa MG, Mato RB, Cocero MJ (2008) Modelling steam distillation of essential oils: application to lavandin super oil. AIChEJ 54:909–917

    Article  CAS  Google Scholar 

  • Chatzopolou PS, Goliaris AH, Katsiotis T (2003) Contribution to the analysis of the volatile constituents from some lavender and lavandin cultivars grown in Greece. Sci Pharm 71:229–234

    Google Scholar 

  • Chemat F, Lucchesi ME, Smadja J et al (2006) Microwave accelerated steam distillation of essential oil from lavender: a rapid, clean and environmentally friendly approach. Anal Chim Acta 555:157–160

    Article  CAS  Google Scholar 

  • Cherrat L, Espina L, Bakkali M et al (2014) Chemical composition, antioxidant and antimicrobial properties of Mentha pulegium, Lavandula stoechas and Satureja calamintha Scheele essential oils and an evaluation of their bactericidal effect in combined processes. Innov Food Sci Emerg Technol 22:221–229

    Article  CAS  Google Scholar 

  • Chhetri BK, Nasser AAA, Setzer WN (2015) A survey of chemical compositions and biological activities of Yemen aromatic medicinal plants. Medicines 2:67–92

    Article  CAS  Google Scholar 

  • Chizzola R (2013) Regular monoterpenes and sesquiterpenes (essential oils). In: Ramawat KG, Mérillon JM (eds) Natural products. Springer, Berlin Heidelberg, pp 2973–3003

    Chapter  Google Scholar 

  • Chograni H, Zaouali Y, Rajeb C et al (2010) Essential oil variation among natural populations of Lavandula multifida L. (Lamiaceae). Chem Biodivers 7:933–942

    Article  CAS  PubMed  Google Scholar 

  • Chograni H, Zaouali Y, Boussaid M (2012) Genetic diversity and chemical polymorphism of Tunisian Lavandula multifida L. (Lamiaceae) populations. Afr J Biotechnol 11:14858–14867

    CAS  Google Scholar 

  • Cong Y, Abulizi P, Zhi L, Wang X et al (2008) Chemical composition of the essential oil of Lavandula angustifolia from Xinjiang, China. Chem Nat Compd 44:810

    Article  CAS  Google Scholar 

  • Costa P, Grosso C, Gonçalves S et al (2012) Supercritical fluid extraction and hydrodistillation for the recovery of bioactive compounds from Lavandula viridis L’Hér. Food Chem 135:112–121

    Article  CAS  Google Scholar 

  • Costa P, Gonçalves S, Valentão P et al (2013) Metabolic profile and biological activities of Lavandula pedunculata subsp. lusitanica (Chaytor) Franco: studies on the essential oil and polar extracts. Food Chem 141:2501–2506

    Article  CAS  PubMed  Google Scholar 

  • Da Porto C, Decorti D, Kikic I (2009) Flavour compounds of Lavandula angustifolia L. to use in food manufacturing: comparing of three different extraction methods. Food Chem 112:1072–1078

    Article  CAS  Google Scholar 

  • Danh LT, Han LN, Triet NDA et al (2013) Comparison of chemical composition, antioxidant and antimicrobial activity of lavender (Lavandula angustifolia L.) essential oils extracted by supercritical CO2, hexane and hydrodistillation. Food Bioprocess Technol 6:3481–3489

    Article  CAS  Google Scholar 

  • De Pascual TJ, Ovejero J, Anaya J et al (1989) Chemical composition of the Spanish spike oil. Planta Med 55:398

    Article  Google Scholar 

  • Djenane D, Aïder M, Yangüela J et al (2012) Antioxidant and antibacterial effects of Lavandula and Mentha essential oils in minced beef inoculated with E. coli O157:H7 and S. aureus during storage at abuse refrigeration temperature. Meat Sci 92:667–674

    Article  CAS  PubMed  Google Scholar 

  • Dob T, Dahmane D, Agli M, Chelghoum C (2006) Essential oil composition of Lavandula stoechas from Algeria. Pharm Biol 44:60–64

    Article  CAS  Google Scholar 

  • Duškova E, Dušek K, Indrák P et al (2016) Postharvest changes in essential oil content and quality of lavender flowers. Ind Crop Prod 79:225–231

    Article  CAS  Google Scholar 

  • Eikani MH, Golmohammad F, Shokrollahzadev S et al (2006) Superheated water extraction of Lavandula latifolia Medik volatiles: comparison with conventional techniques. J Essent Oil Res 20:482–487

    Article  Google Scholar 

  • Erland LAE, Mahmoud SS (2016) Lavender (Lavandula angustifolia) oils. In: Preedy VE (ed) Essential oils in food preservation, flavor and safety. Academic, Amsterdam, pp 501–507

    Chapter  Google Scholar 

  • European Union, Council of Europe (2008) European Pharmacopoeia 6th edn, vol. 2. Strassbourg

  • Fakhari AR, Salehi P, Heydari R et al (2005) Hydrodistillation-headspace solvent microextraction, a new method for analysis of the essential oil components of Lavandula angustifolia Mill. J Chromatogr A 1098:14–18

    Article  CAS  PubMed  Google Scholar 

  • Figueiredo AC, Barroso JG, Pedro LG et al (1995) Composition of the essential oil of Lavandula pinnata L. fil. var. pinnata grown on Madeira. Flavour Fragr J 10:93–96

    Article  CAS  Google Scholar 

  • Filly A, Fabiano-Tixier AS, Loius C et al (2016) Water as a green solvent combined with different techniques for extraction of essential oil from lavender flowers. C R Chim 19:707–717

    Article  CAS  Google Scholar 

  • Flores CR, Pennec A, Nugier-Chauvin C et al (2014) Chemical composition and antibacterial activity of essential oils extracted from plants cultivated in Mexico. J Mex Chem Soc 58:452–455

    CAS  Google Scholar 

  • Garciá Vallejo MI (1992) Aceites esenciales de las Lavandulas Ibéricas. Ensayo de la quimiotaxonomia.Thesis Doctoral, Universidad Complutense de Madrid, Facultad de Biologia

  • Giray SE, Kirici S, Alpaslan Kaya D et al (2008) Comparing the effect of sub-critical water extraction with conventional extraction methods on the chemical composition of Lavandula stoechas. Talanta 74:930–935

    Article  CAS  PubMed  Google Scholar 

  • Gonçalves S, Serra H, Nogueira JMF et al (2008) Headspace-SPME of in vitro shoot-cultures and micropropagated plants of Lavandula viridis. Biol Plantarum 52:133–136

    Article  Google Scholar 

  • González-Coloma A, Martín-Benito D, Mohamed N et al (2006) Antifeedant effects and chemical composition of essential oils from different populations of Lavandula luisieri L. Biochem Syst Ecol 34:609–616

    Article  CAS  Google Scholar 

  • González-Coloma A, Delgado F, Rodilla JM et al (2011) Chemical and biological profiles of Lavandula luisieri essential oils from western Iberia Peninsula populations. Biochem Syst Ecol 39:1–8

    Article  CAS  Google Scholar 

  • González-Rivera J, Duce C, Falconieri D et al (2016) Coaxial microwave assisted hydrodistillation of essential oils from five different herbs (lavender, rosemary, sage, fennel seeds and clove buds): chemical composition and thermal analysis. Innov Food Sci Emerg Technol 33:308–318

    Article  CAS  Google Scholar 

  • Gören AC, Topçu B, Bilsel G, Bilsel M et al (2002) The chemical constituents and biological activity of essential oil of Lavandula stoechas ssp. stoechas. Z Naturforsch 57:797–800

    Google Scholar 

  • Guitton Y, Nicole F, Moja S et al (2010) Differential accumulation of volatile terpene and terpene synthase mRNAs during lavender (Lavandula angustifolia ad L. × intermedia) inflorescence development. Physiol Plant 138:150–163

    Article  CAS  PubMed  Google Scholar 

  • Hamad KJ, Al-Shaheen SJA, Kaskoos RA et al (2013) Essential oil composition and antioxidant activity of Lavandula angustifolia from Irak. Int Res J Pharm 4:117–120

    CAS  Google Scholar 

  • Hanamanthagouda MS, Kakkalameli SB, Naik PM et al (2010) Essential oils of Lavandula bipinnata and their antimicrobial activities. Food Chem 118:836–839

    Article  CAS  Google Scholar 

  • Harborne JB, Williams C (2002) Phytochemistry of the genus Lavandula. In: Lis-Balchin M (ed) Lavender: the genus Lavandula: medicinal and aromatic plants-industrial profiles. Taylor and Francis, London, pp 86–99

    Google Scholar 

  • Hassanpouraghdam MB, Hassani A, Vojodi L et al (2011) Essential oil constituents of Lavandula officinalis Chaix from Northwest Iran. Chemija 22:167–171

    CAS  Google Scholar 

  • Hassiotis CN (2010) Chemical compounds and essential oil release through decomposition process from Lavandula stoechas in Mediterannean region. Biochem Syst Ecol 38:493–501

    Article  CAS  Google Scholar 

  • Hassiotis CN, Tarantilis PA, Daferera D et al (2010) Etherio, a new variety of Lavandula angustifolia with improved essential oil production and composition from natural selected genotypes growing in Greece. Ind Crop Prod 32:77–82

    Article  CAS  Google Scholar 

  • Hassiotis CN, Ntana F, Lazari DM et al (2014) Environmental and developmental factors affect essential oil production and quality of Lavandula angustifolia during flowering period. Ind Crop Prod 62:359–366

    Article  CAS  Google Scholar 

  • Herraiz-Peñalver D, Cases MÁ, Varela F et al (2013) Chemical characterization of Lavandula latifolia Medik. essential oil from Spanish wild populations. Biochem Syst Ecol 46:59–68

    Article  CAS  Google Scholar 

  • Imelouane B, Elbachiri A, Wathelet JP et al (2010) Chemical composition, cytotoxic and antioxidant activity of the essential oil of L. dentata. World J Chemistry 5:103–110

    CAS  Google Scholar 

  • ISO 3515:1987 Oil of French Lavender (Lavandula angustifolia P. Miller)

  • ISO 8902:1999(E) Oil of lavandin Grosso (Lavandula angustifolia Miller × Lavandula latifolia Medikus), French type

  • ISO 4719:1999(E) Oil of spike lavender [Lavandula latifolia (L.f.) Medikus], Spanish type

  • ISO 3054:2001(E) Oil of lavandin Abrial (Lavandula angustifolia Miller × Lavandula latifolia Medikus), French type

  • Jianu C, Pop G, Gruia AT et al (2013) Chemical composition and antimicrobial activity of essential oils of lavender (Lavandula angustifolia) and lavandin (Lavandula × intermedia) grown in western Romania. Int J Agric Biol 15:772–776

    CAS  Google Scholar 

  • Julio LF, Martín L, Muñoz R et al (2014) Comparative chemistry and insect antifeedant effects of conventional (Clevenger and Soxhlet) and supercritical extracts (CO2) of two Lavandula luisieri populations. Ind Crop Prod 58:25–30

    Article  CAS  Google Scholar 

  • Kaloustian J, Pauli A-M, Pastor J (2000) Evolution on camphor and others components in the essential oils of two labiatae species during the biological cycle. Analusis 28:308–315

    Article  CAS  Google Scholar 

  • Kara N, Baydar H (2013) Determination of lavender and lavandin cultivars (Lavandula sp.) containing high quality essential oil in Isparta, Turkey. Turk J Field Crops 18:58–65

    Google Scholar 

  • Karapandzova M, Cvetkovikj I, Stefkov G et al (2012) The influence of duration of the distillation of fresh and dried flowers on the essential oil composition of lavandin cultivated in Republic of Macedonia. Maced Pharm Bull 58:31–38

    Google Scholar 

  • Kaya DA, Inan M, Giray ES et al (2012) Diurnal, ontogenetic and morphogenetic variability of L. stoechas L.ssp. stoechas in East Mediterranean Region. Rev Chim 63:749–753

    CAS  Google Scholar 

  • Kim N-S, Lee D-S (2002) Comparison of different extraction methods for the analysis of fragrances from Lavandula species by gas chromatography-mass spectrometry. J Chromatogr A 982:31–47

    Article  CAS  PubMed  Google Scholar 

  • Kiran Babu GD, Singh B (2012) Characteristics variation of lavender oil produced by different hydrodistillation techniques. Compr Bio Nat Prod 8:122–136

    Google Scholar 

  • Kiran Babu GD, Thakur V, Singh B (2016) Variability in the composition of Lavandula angustifolia extracts due to extraction methods. J Herbs Spices Med Plants 22:173–182

    Article  Google Scholar 

  • Kırmızıbekmez H, Demirci B, Yeşilada E et al (2009) Chemical composition and antimicrobial activity of the essential Oils of Lavandula stoechas L. ssp. stoechas growing wild in Turkey. Nat Prod Commun 4:1001–1006

    PubMed  Google Scholar 

  • Kulkarni RR, Pawar PV, Joseph MP et al (2013) Lavandula gibsoni and Plectranthus mollis essential oils: chemical analysis and insect control activities against Aedes aegypti, Anopheles stephensi and Culex quinquefasciatus. J Pest Sci 86:713–718

    Article  Google Scholar 

  • La Bella S, Tuttolomondo T, Dugo G et al (2015) Composition and variability of the essential oil of the flowers of Lavandula stoechas from various geographical sources. Nat Prod Commun 10:2001–2004

    PubMed  Google Scholar 

  • Lane A, Boecklemann A, Woronuk GN et al (2010) A genomics resource for investigating regulation of essential oil production in Lavandula angustifolia. Planta 231:835–845

    Article  CAS  PubMed  Google Scholar 

  • Lange M, Ahkam A (2013) Metabolic engineering of plant monoterpenes, sesquiterpenes and diterpenes-current status and future opportunities. Plant Biotechnol J 11:169–196

    Article  CAS  PubMed  Google Scholar 

  • Lesage-Meessen L, Bou M, Sigoillot J-C et al (2015) Essential oils and distilled straws of lavender and lavandin: a review of current use and potential application in white biotechnology. Appl Microbiol Biotechnol 99:3375–3385

    Article  CAS  PubMed  Google Scholar 

  • Lis-Balchin M (2002) Chemical composition of essential oils from different species, hybrids and cultivars of Lavandula. In: Lavender: the genus Lavandula. Taylor Francis, London, pp 251-262

  • Lis-Balchin M (2012) Lavender. In: Peter KV (ed) Handbook of herbs and spices. Woodhead Publishing Limited, Cambridge, pp 329–347

    Chapter  Google Scholar 

  • Maia NB, Bovi OA, Perecin MB et al (2004) New crops with potential to produce essential oil with high linalool content helping preserve rosewood, an endangered Amazon species. Acta Hortic 629:39–43

    Article  CAS  Google Scholar 

  • Mantovani ALL, Vieira GPG, Cunha WR et al (2013) Chemical composition, antischistosomal and cytotoxic effects of the essential oil of Lavandula angustifolia grown in Southeastern Brazil. Rev Bras Farmacogn 23:877–884

    Article  CAS  Google Scholar 

  • Martucci JF, Gende LB, Neira LM et al (2015) Oregano and lavender essential oils as antioxidant and antimicrobial additives of biogenic gelatin films. Ind Crop Prod 71:205–213

    Article  CAS  Google Scholar 

  • Masetto MA, Deschamps C, Mogor AF et al (2011) Yield and composition of essential oil from inflorescences and leaves of lavender (L. dentata L.) in different flower development stages and harvest times. Rev Bras Plantas Med 13:413–421

    Article  CAS  Google Scholar 

  • Méndez-Tovar I, Sponza S, Asensio-S-Manzanera MC et al (2015) Volatile fraction differences for Lamiaceae species using different extraction methodologies. J Essent Oil Res 27:497–505

    Article  CAS  Google Scholar 

  • Méndez-Tovar I, Novak J, Sponza S et al (2016) Variability in essential oil composition of wild populations of Labiatae species collected in Spain. Ind Crop Prod 79:18–28

    Article  CAS  Google Scholar 

  • Messaoud C, Chograni H, Boussaid M (2012) Chemical composition and antioxidant activities of essential oils and methanol extracts of three wild Lavandula L. species. Nat Prod Res 26:1976–1984

    Article  CAS  PubMed  Google Scholar 

  • Miladinović DL, Ilić BS, Mihajilov-Krstev TM et al (2012) Investigation of the chemical composition–antibacterial activity relationship of essential oils by chemometric methods. Anal Bional Chem 43:1007–1018

    Article  CAS  Google Scholar 

  • Milina R, Mustafa Z, Stanev S et al (2012) Headspace gas chromatographic analysis of Bulgarian Lavandula angustifolia Mill. herbs. I. Optimization of the analysis conditions. Scientific Works of the University (Bulgarian) 51:50–56

    Google Scholar 

  • Mothana RA, Alsaid MS, Hasoon SS et al (2012) Antimicrobial and antioxidant activities and gas-chromatography mass spectrometry (GC/MS) analysis of the essential oils of Ajuga bracteosa Wall.ex Benth. and Lavandula dentata L. growing wild in Yemen. J Med Plant Res 6:3066–3071

    CAS  Google Scholar 

  • Msaada K, Salem N, Tammar S et al (2012) Essential oil composition of Lavandula dentata, L. stoechas and L. multifida cultivated in Tunisia. J Essent Oil Bear Pl 15:1030–1039

    Article  CAS  Google Scholar 

  • Muñoz-Bertomeu J, Arrillaga I, Segura J (2007) Essential oil variation within and among natural populations of Lavandula latifolia and its relation to their ecological areas. Biochem Syst Ecol 35:479–488

    Article  CAS  Google Scholar 

  • N’Dédianhoua Soro K, Moutaouakil K, El-Hilali F et al (2014) Chemical composition and antibacterial power of Lavandula multifida L. essential oil against multiresistant strains of Escherichia coli, Pseudomonas aeruginosa and Klebsiella pneumoniae isolated in hospital. IJISR 9:464–472

    Google Scholar 

  • Nasser AAA, Wurster M, Alkaf AG et al (2013) Lavandula pubescens Decne-a potential source of carvacrol-rich essential oil in Yemen. Univ Aden J Nat Appl Sci 17:1–5

    Google Scholar 

  • NIIR (2011) The complete technology book of essential oils (aromatic chemicals). Asia Pacific Business Press Inc, Delhi

    Google Scholar 

  • Nogueira JMF, Romano A (2002) Essential oils from micropropagated plants of Lavandula viridis. Phytochem Anal 13:4–7

    Article  CAS  PubMed  Google Scholar 

  • Palá-Paúl J, Brophy JJ, Goldsack RJ et al (2004) Analysis of the volatile components of Lavandula canariensis (L.) Mill., a Canary Islands endemic species, growing in Australia. Biochem Syst Ecol 32:55–62

    Article  CAS  Google Scholar 

  • Panda H (2005) Aromatic plants. Cultivation, processing and uses. Asia Pacific Business Press Inc, Delhi

    Google Scholar 

  • Paolini J, Leandri C, Desjobert J-M et al (2008) Comparison of liquid–liquid extraction with headspace methods for the characterization of volatile fractions of commercial hydrolats from typically Mediterranean species. J Chromatogr A 1193:38–49

    Article  CAS  Google Scholar 

  • Papachristos DP, Karamanoli KI, Stamopoulos DC et al (2004) The relationship between the chemical composition of three essential oils and their insecticidal activity against Acanthoscelides obtectus (Say). Pest Manag Sci 60:514–520

    Article  CAS  PubMed  Google Scholar 

  • Périno-Issartier S, Ginies C, Cravotto G et al (2013) A comparison of essential oils obtained from lavandin via different extraction processes: ultrasound, microwave, turbohydrodistillation, steam and hydrodistillation. J Chromatogr A 1305:41–47

    Article  PubMed  CAS  Google Scholar 

  • Pombal S, Rodrigues CF, Araújo JP et al (2016) Antibacterial and antioxidant activity of Portuguese Lavandula luisieri (Rozeira) Rivas-Martinez and its relation with their chemical composition. Springerplus 5:1711. doi:10.1186/s40064-016-3415-7

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Raina AP, Negi KS (2012) Comparative essential oil composition of Lavandula species from India. J Herb Spice Med Plants 18:268–273

    Article  CAS  Google Scholar 

  • Ravid U (2008) Enantiomeric distribution of odorous oxygenated monoterpenes in aromatic plants. In: Ikan R (ed) Selected topics in the chemistry of natural products. World Scientific Publishing, Singapore, pp 155–189

    Google Scholar 

  • Renaud ENC, Denys CJ, Simon JE (2001) Essential oil quantity and composition from 10 cultivars of organically grown lavender and lavandin. J Essent Oil Res 13:269–273

    Article  CAS  Google Scholar 

  • Reyes-Jurado F, Franco-Vega A, Ramírez-Corona N et al (2015) Essential oils: antimicrobial activities, extraction methods, and their modeling. Food Eng Res 7:275–297

    Article  CAS  Google Scholar 

  • Ristorcelli D, Tomi F, Casanova J (1998) 13C-NMR as a tool for identification and enantiomeric differentiation of major terpenes exemplified by the essential oil of Lavandula stoechas L. ssp. stoechas. Flavour Fragr J 13:154–158

    Article  CAS  Google Scholar 

  • Robu S, Aprotosoaie AC, Spac A et al (2011) Studies regarding chemical composition of lavender volatile oils. Rev Med Chir Soc Med Nat Iasi 115:584–589

    PubMed  Google Scholar 

  • Rodrigues N, Malheiro R, Casal S (2012) Influence of spike lavender (Lavandula latifolia Med.) essential oil in the quality, stability and composition of soybean oil during microwave heating. Food Chem Toxicol 50:2894–2901

    Article  CAS  PubMed  Google Scholar 

  • Saadi A, Brada M, Kouidri M et al (2016) Chemical composition and content of essential oil of Lavandula multifida from Algeria. Chem Nat Compd 52:162–164

    Article  CAS  Google Scholar 

  • Sajfrtova M, Sovova H, Karban J et al (2013) Effect of separation method on chemical composition and insecticidal activity of Lamiaceae isolates. Ind Crop Prod 47:69–77

    Article  CAS  Google Scholar 

  • Salido S, Altarejos J, Nogueras M et al (2004) Chemical composition and seasonal variations of spike lavender oil from Southern Spain. J Essent Oil Res 16:206–210

    Article  CAS  Google Scholar 

  • Se YO (2013) Fast gas chromatography–surface acoustic wave sensor: an effective tool for discrimination and quality control of Lavandula species. Sens Actuat B Chem 182:223–231

    Article  CAS  Google Scholar 

  • Seidler-Lozykowska K, Mordalski R, Kucharski W et al (2014) Yielding and quality of lavender flowers (Lavandula angustifolia Mill. 0 from organic cultivation. Acta Sci Pol Hortorum Cultus 13:173–183

    Google Scholar 

  • Sellam K, Ramchoun M, Alem C et al (2013) Biological investigations of antioxidants-antimicrobial properties and chemical composition of essential oil from Lavandula multifida. Oxid Antioxid Med Sci 2:211–216

    Article  Google Scholar 

  • Skoula M, Abidi C, Kokkalou E (1996) Essential oil variation of Lavandula stoechas L. ssp. stoechas growing wild in Crete (Greece). Biochem Syst Ecol 24:255–260

    Article  CAS  Google Scholar 

  • Smigielski K, Raj A, Krosowiak K et al (2009) Chemical composition of the essential oil of Lavandula angustifolia cultivated in Poland. J Essent Oil Bear Pl 12:338–347

    Article  CAS  Google Scholar 

  • Stanev S (2010) Evaluation of the stability and adaptability of the Bulgarian lavender (Lavandula angustifolia Mill.) sorts yield. Agric Sci Technol 2:121–123

    Google Scholar 

  • Stanev S, Zagorcheva T, Atanassiov I (2016) Lavender cultivation in Bulgaria-21st century developments, breeding challenges and oppurtunities. Bulg J Agric Sci 22:584–590

    Google Scholar 

  • Stanojevic L, Stanković M, Cakić M et al (2011) The effect of hydrodistillation techniques on yield, kinetics, composition and antimicrobial activity of essential oils from flowers of Lavandula officinalis L. Hem Ind 65:455–463

    Article  CAS  Google Scholar 

  • Surburg H, Panten J (2006) Common fragrance and flavor materials. Preparation, properties and uses. In: 5th completely revised and enlarged edition. Wiley, Weinheim

  • Tarek N, Hassan HM, AbdelGhani SMM et al (2014) Comparative chemical and antimicrobial study of nine essential oils obtained from medicinal plants growing in Egypt. Beni Seuf Univ J Appl Sci 3:149–156

    Google Scholar 

  • Torabbeigi M, Azar AP (2013) Analysis of essential oil compositions of Lavandula angustifolia by HS-SPME and MA-HS-SPME followed by GC and GC-MS. Acta Chromatogr 25:571–579

    Article  CAS  Google Scholar 

  • Tuttolomondo T, Dugo G, Ruberto G et al (2015) Agronomical evaluation of Sicilian biotypes of Lavandula stoechas L. spp. stoechas and analysis of the essential oils. J Essent Oil Res 27:115–124

    Article  CAS  Google Scholar 

  • Tzakou O, Bazos I, Yannitsaros A (2009) Essential oil composition and enantiomeric distribution of fenchone and camphor of L. cariensis and L. stoechas subsp. stoechas grown in Greece. Nat Prod Commun 4:1103–1106

    CAS  PubMed  Google Scholar 

  • Varona S, Rodríguez Rojo S, Martín Á et al (2013) Antimicrobial activity of lavandin essential oil formulations against three pathogenic food-borne bacteria. Ind Crop Prod 42:243–250

    Article  CAS  Google Scholar 

  • Verma RS, Rahman LU, Chanotiya CS et al (2010) Essential oil composition of Lavandula angustifolia Mill. cultivated in the mid hills of Uttarakhand. India. J Serb Chem Soc 75:343–348

    Article  CAS  Google Scholar 

  • Viuda-Martos M, Mohamady MA, Fernández-López J et al (2011) In vitro antioxidant and antibacterial activities of essentials oils obtained from Egyptian aromatic plants. Food Control 22:1715–1722

    Article  CAS  Google Scholar 

  • Wesolowska A, Jadczak D, Grzeszczuk M (2010) Influence of distillation time on the content and composition of essential oil isolated from lavender (Lavandula angustifolia Mill.). Herba Pol 56:25–36

    Google Scholar 

  • Wiesenfeld E (1999) Aroma profiles of various lavandula species, Noville, South Hackensack, NJ, USA, http://www.sisweb.com.referenc/applnote/noville.htm

  • Yazdani E, Sendi JJ, Aliakbar A et al (2013) Effect of Lavandula angustifolia essential oil against lesser mulberry pyralid Glyphodes pyloalis Walker (Lep: Pyralidae) and identification of its major derivatives. Pestic Biochem Physiol 107:250–257

    Article  CAS  Google Scholar 

  • Zagorcheva T, Stanev S, Rusanov K et al (2013) Comparative GC/MS analysis of lavender (Lavandula angustifolia Mill.) inflorescence and essential oil volatiles. Agri Sci Technol 5:459–462

    Google Scholar 

  • Zheljazkov VD, Astatkie T, Hristov AN (2012) Lavender and hyssop productivity, oil content, and bioactivity as a function of harvest time and drying. Ind Crop Prod 36:222–228

    Article  CAS  Google Scholar 

  • Zheljazkov VD, Cantrell CL, Astatkie T et al (2013) Distillation time effect on lavender essential oil yield and composition. J Oleo Sci 62:195–199

    Article  CAS  PubMed  Google Scholar 

  • Zhi-ling C, Jian-ping C, Hui-lin C et al (2011) Research on the extraction of plant volatile oils. Proc Environ Sci 8:426–432

    Article  CAS  Google Scholar 

  • Zrira S, Benjilali B (2003) The constituents of the oils of Lavandula stoechas L. ssp. atlantica Br.-Bl. and L. stoechas ssp. stoechas from Morocco. J Essent Oil Res 15:68–69

    Article  CAS  Google Scholar 

  • Zuzarte M, Gonçalves MJ, Cavaleiro C et al (2009) Chemical composition and antifungal activity of the essential oils of Lavandula pedunculata (Miller) Cav. Chem Biodivers 6:1283–1290

    Article  CAS  PubMed  Google Scholar 

  • Zuzarte M, Dinis AM, Cavaleiro C et al (2010) Trichomes, essential oils and in vitro propagation of Lavandula pedunculata (Lamiaceae). Ind Crop Prod 32:580–587

    Article  CAS  Google Scholar 

  • Zuzarte M, Gonçalves MJ, Cavaleiro C et al (2011) Chemical composition and antifungal activity of the essential oils of Lavandula viridis L’Hér. J Med Microbiol 60:612–618

    Article  CAS  PubMed  Google Scholar 

  • Zuzarte M, Gonçalves MJ, Cruz MT et al (2012a) Lavandula luisieri essential oil as a source of antifungal drugs. Food Chem 135:1505–1510

    Article  CAS  PubMed  Google Scholar 

  • Zuzarte M, Vale-Silva L, Gonçalves MJ et al (2012b) Antifungal activity of phenolic-rich Lavandula multifida L. essential oil. Eur J Clin Microbiol Infect Dis 31:1359–1366

    Article  CAS  PubMed  Google Scholar 

  • Zuzarte M, Gonçalves MJ, Cavaleiro C et al (2013) Antifungal and anti-inflammatory potential of Lavandula stoechas and Thymus herba-barona essential oils. Ind Crop Prod 44:97–103

    Article  CAS  Google Scholar 

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Aprotosoaie, A.C., Gille, E., Trifan, A. et al. Essential oils of Lavandula genus: a systematic review of their chemistry. Phytochem Rev 16, 761–799 (2017). https://doi.org/10.1007/s11101-017-9517-1

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