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Mechanisms of Antiradical Activity of 2,3,5,6,8-Pentahydroxy-7-Ethyl-1,4-Naphthoquinone (A Review)

  • MOLECULAR-BIOLOGICAL PROBLEMS OF DRUG DESIGN AND MECHANISM OF DRUG ACTION
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Pharmaceutical Chemistry Journal Aims and scope

The role of the antioxidant properties of 2,3,5,6,8-pentahydroxy-7-ethyl-1,4-naphthoquinone in the manifestation of its pharmacological effects is reviewed. Issues with pleiotropic cellular-molecular mechanisms of echinochrome A action are considered with emphasis on the unique antioxidant activity of 2,3,5,6,8-pentahydroxy-7-ethyl-1,4-naphthoquinone. These properties in combination with a low destructive potential account for the prospects of expanding the therapeutic use of echinochrome A.

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  1. Altai State Medical University, Ministry of Health of the Russian Federation, Barnaul, Altai Krai, 656038, Russia

    O. S. Talalaeva, Ya. F. Zverev & V. M. Bryukhanov

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  1. O. S. Talalaeva
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 50, No. 6, pp. 3 – 7, June, 2016.

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Talalaeva, O.S., Zverev, Y.F. & Bryukhanov, V.M. Mechanisms of Antiradical Activity of 2,3,5,6,8-Pentahydroxy-7-Ethyl-1,4-Naphthoquinone (A Review). Pharm Chem J 50, 353–357 (2016). https://doi.org/10.1007/s11094-016-1450-x

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