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Influence of Plasma Treatments on the Hemocompatibility of PET and PET + TiO2 Films

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A Correction to this article was published on 06 June 2020

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Abstract

A dielectric barrier discharge (DBD) in helium was used to ameliorate the interface between the blood and the surface of polymeric implants: polyethylene terephthalate (PET) and PET with titanium oxide (PET + TiO2). A higher crystallinity degree was found for the DBD treated samples. The wettability of polymers was improved after the treatment. The chemical composition, analyzed by infrared spectroscopy was preserved during the DBD treatment. The surface modifications have been correlated with polymers hemocompatibility. Concerning the polymer surface–blood interaction, the treatment induced a decrease of the interfacial tension between the blood components and the treated surfaces. The in vitro tests of hemocompatibility showed no perturbation in the blood composition when the polymer samples are present in the blood volume. An interesting result is related to the whole blood clotting time that shows a dramatic increase on the treated surfaces. Moreover, the coagulation kinetics on the treated surfaces is modified.

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  • 06 June 2020

    The Editor-in-Chief would like to alert readers that due to an administrative error, the article [1] has been republished in the same journal as [2]. The correct citation for this article should be the original publication [1].

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Acknowledgments

The authors thank PhD Cristina Morariu, Hematology Laboratory, Military Hospital, Iasi, Romania, for its help with the hemocompatibility tests. This work was supported by the Romanian National University Research Council (CNCSIS) under Grant 1461/2005–2006.

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Authors and Affiliations

  1. Plasma Physics Laboratory, Faculty of Physics, Alexandru Ioan Cuza University, Blvd. Carol I, No. 11, 700506, Iasi, Romania

    Ionut Topala, Nicoleta Dumitrascu & Valentin Pohoata

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  1. Ionut Topala
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  2. Nicoleta Dumitrascu
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  3. Valentin Pohoata
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Correspondence to Ionut Topala.

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Topala, I., Dumitrascu, N. & Pohoata, V. Influence of Plasma Treatments on the Hemocompatibility of PET and PET + TiO2 Films. Plasma Chem Plasma Process 28, 535–551 (2008). https://doi.org/10.1007/s11090-008-9136-0

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  • DOI: https://doi.org/10.1007/s11090-008-9136-0

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