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Metastatic meningiomas: an unusual clinical and pathological diagnosis with highly variable outcome

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Abstract

Metastatic meningioma is a rare situation. We conducted a retrospective study from our databases and identified cases of metastatic meningioma. We report three presentations of patients with medical history of surgical removal of meningioma presenting several years later a liver tumor with bone metastasis or multiple lung tumors. These observations highlight the difficulty of the clinical and pathological diagnosis and the absence of consideration of metastatic state for histologically “benign” but clinically aggressive meningiomas in the current WHO 2007 classification of meningiomas. We also reviewed published cases of metastatic meningiomas since they are clearly distinguished from haemangiopericytoma.

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Acknowledgments

We would like to thank Pr Jean-Louis Stephan for his help with the bibliographic research and Mr Niall Finn for his help in English language.

Conflict of interest

None.

Ethical standards

All patients provided informed consent, local ethics committee review board was consulted and agreed this study, which was performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki.

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Authors and Affiliations

  1. Service d’anatomie et cytologie pathologiques, Centre Hospitalier Universitaire de Saint-Etienne, Hôpital Nord., 42055, Saint Etienne Cedex2, France

    Fabien Forest, Sid-Ali Berremila, Basile Pasquier & Michel Péoc’h

  2. Service d’anatomie et cytologie pathologiques, Centre Hospitalier de Roanne, 28, rue de Charlieu., BP 511, 42328, Roanne Cedex, France

    Cezar Gyenes

  3. Service de neurochirurgie, Centre Hospitalier Universitaire de Saint-Etienne, Hôpital Nord., 42055, Saint Etienne Cedex2, France

    Carole Ginguéné

  4. Service de chirurgie digestive, Centre Hospitalier Universitaire de Saint-Etienne, Hôpital Nord., 42055, Saint Etienne Cedex2, France

    Radwan Kassir & Jack Porcheron

  5. Service de chirurgie générale et thoracique, Centre Hospitalier Universitaire de Saint-Etienne, Hôpital Nord., 42055, Saint Etienne Cedex2, France

    Abdulrazzaq Sulaiman

Authors
  1. Fabien Forest
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  2. Sid-Ali Berremila
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  9. Michel Péoc’h
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Correspondence to Fabien Forest.

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Forest, F., Berremila, SA., Gyenes, C. et al. Metastatic meningiomas: an unusual clinical and pathological diagnosis with highly variable outcome. J Neurooncol 120, 411–421 (2014). https://doi.org/10.1007/s11060-014-1567-2

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  • DOI: https://doi.org/10.1007/s11060-014-1567-2

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