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Cutaneous Cryptococccosis Due to Cryptococcus gattii in Immunocompetent Hosts: Case Report and Review

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Abstract

Cutaneous cryptococcosis caused by C. gattii, in immunocompent patients is a rare manifestation of disease, and may be one of the first manifestations of disseminated cryptococcosis. We report a case of disseminated cryptococcosis caused by Cryptococcus gattii presenting as cutaneous lesions in an immunocompetent patient. Previously to our report, only five cases of cutaneous involvement by Cryptococcus gattii in immunocompetent patients have been reported in the literature. Risk factors for C. gattii infection included exposure to the eucalypt reservoirs in tropical and subtropical areas. Skin involvement corresponded to the disseminated form of cryptococcosis in the majority of patients, and commonly affected the face and neck with different morphologies including papules, pustules, plaques, ulcers, subcutaneous masses, cellulitis or acneiform lesions. Due to the severity of this infection and the life threatening condition that it represents, clinicians must be aware that cutaneous involvement may be one of the first manifestations of disseminated cryptococcosis caused by C. gattii especially in patients living and coming from endemic areas.

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References

  1. A Casadevall JR Perfect (1998) Cryptococcus neoformans ASM Press Washington, D.C

    Google Scholar 

  2. DH Ellis TJ Pfeiffer (1990) ArticleTitleEcology, life cycle and infectious propagule of Cryptococcus neoformans Lancet 336 923–925 Occurrence Handle1:STN:280:By6D3MvivFc%3D Occurrence Handle1976940

    CAS  PubMed  Google Scholar 

  3. TC Sorrell (2001) ArticleTitleCryptococcus neoformans variety gattii Med. Mycol. 39 155–168 Occurrence Handle1:STN:280:DC%2BD3M3ltVCksQ%3D%3D Occurrence Handle11346263

    CAS  PubMed  Google Scholar 

  4. B Speed D Dunt (1995) ArticleTitleClinical and host differences between infections with the two varieties of Cryptococcus neoformans Clin. Infect. Dis. 21 28–34 Occurrence Handle1:STN:280:BymD28rmtVw%3D Occurrence Handle7578756

    CAS  PubMed  Google Scholar 

  5. PR Peachey PO Gubbins RE Martin (1998) ArticleTitleThe association between cryptococcal variety and immunocompetent and immunocompromised hosts Pharmacology 18 255–264 Occurrence Handle1:STN:280:DyaK1c3gsVOjtw%3D%3D

    CAS  Google Scholar 

  6. X Xiuijao X Ai’e (2005) ArticleTitleTwo cases of cutaneous cryptococcosis Mycoses 48 238–241

    Google Scholar 

  7. CS Lacaz EM Heins-Vaccari GL Hernández-Arriagada (2002) ArticleTitlePrimary cutaneous cryptococcosis due to Cryptococcus neoformans var. gattii serotype B, in an immunocompetent patient Rev. Inst. Med. Trop. 44 225–228

    Google Scholar 

  8. LC Severo IB Zardo AT Londero (2001) ArticleTitleCutaneous cryptococcosis due to Cryptococcus neoformans var. gattii Rev. Iberoame Micol. 18 200–201 Occurrence Handle1:STN:280:DC%2BD2cris1WltQ%3D%3D

    CAS  Google Scholar 

  9. ID Hamann RJ Gillespie JK Ferguson (1997) ArticleTitlePrimary cryptococcal cellulitis caused by Cryptococcus neoformans var. gattii in an immunocompetent host Aust. J. Dermatol. 38 29–32 Occurrence Handle1:STN:280:ByiC1MfmtVM%3D

    CAS  Google Scholar 

  10. RJ Ridell BR Entwisle (1969) ArticleTitleCryptococcal Granulomata of the Skin in a Patient with Pulmonary and Cerebral Cryptococcosis Aust. J. Dermatol. 10 100–108

    Google Scholar 

  11. DH Ellis TJ Pfeiffer (1990) ArticleTitleNatural habitat of Cryptococcus neoformans var. gattii J. Clin. Microbiol. 28 1642–1644 Occurrence Handle1:STN:280:By%2BA3sfksFU%3D Occurrence Handle2199524

    CAS  PubMed  Google Scholar 

  12. S Chen T Sorrell G Nimmo et al. (2000) ArticleTitleEpidemiology and host- and variety-dependent characteristics of infection due to Cryptococcus neoformans in Australia and New Zealand. Australasian Cryptococcal Study Group Clin. Infect. Dis. 31 499–508 Occurrence Handle1:STN:280:DC%2BD3M%2FksVSlsQ%3D%3D Occurrence Handle10987712

    CAS  PubMed  Google Scholar 

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Correspondence to Luciano Zubaran Goldani.

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Dora, J.M., Kelbert, S., Deutschendorf, C. et al. Cutaneous Cryptococccosis Due to Cryptococcus gattii in Immunocompetent Hosts: Case Report and Review. Mycopathologia 161, 235–238 (2006). https://doi.org/10.1007/s11046-006-0277-5

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  • DOI: https://doi.org/10.1007/s11046-006-0277-5

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