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The key role of the A-site composition of oxy-hydroxyapatites in high-temperature solid–gas exchange reactions

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Abstract

The manufacture of carbonated hydroxyapatite-based bioceramics with control of the composition and microstructure remains challenging and reveals our lack of knowledge regarding the thermal behavior of such materials, particularly at high temperatures under reactive atmospheres. This work lays a foundation for addressing this issue by investigating the solid–gas exchange reactions occurring between oxy-hydroxyapatites (OxHA) and a CO2-rich atmosphere during thermal treatment. Accordingly, OxHA reference powders with different oxygen contents (0 ≤ x ≤ 0.79) were produced, extensively characterized and heat-treated under a CO2-rich atmosphere at 950 °C for 5 h. The results of physicochemical, thermal and microstructural analyses showed that the A-site composition of OxHA controls the exchange reactions: a high initial OH content induced concomitant A-site dehydration and carbonation; conversely, a high OH vacancy content induced A-site hydration as a first step. Furthermore, the specific surface area significantly influenced the solid–gas exchange reactions by controlling their kinetic.

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Acknowledgements

We acknowledge Coralie Laurent from Mines Saint Etienne and Philipe Steyer and Annie Malchère from INSA Lyon for technical help.

Funding

This study was funded by the Auvergne-Rhone Alpes region (ARC2 program, PhD fellowship to SG).

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Authors and Affiliations

  1. Mines Saint-Etienne, Univ Lyon, Univ Jean Monnet, Etablissement Français du Sang, INSERM, U1059 Sainbiose, 42023, Saint-Étienne, France

    Sophie Guillou, Nathalie Douard, Didier Bernache-Assollant & David Marchat

  2. Univ Lyon, INSA Lyon, UCB Lyon 1, CNRS, MATEIS UMR 5510, 7 Avenue Jean Capelle, 69621, Villeurbanne, France

    Solène Tadier & Laurent Gremillard

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  1. Sophie Guillou
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All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by SG, ND and DM. The first draft of the manuscript was written by SG and DM, and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

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Correspondence to Nathalie Douard.

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Guillou, S., Douard, N., Tadier, S. et al. The key role of the A-site composition of oxy-hydroxyapatites in high-temperature solid–gas exchange reactions. J Therm Anal Calorim 147, 13135–13150 (2022). https://doi.org/10.1007/s10973-022-11512-3

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