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Investigation of select radionuclides stability in urine under various conditions for liquid scintillation counting (LSC)

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Abstract

Liquid Scintillation Counting (LSC) gross alpha/beta screening is a valuable tool for providing rapid laboratory response for the analysis of human clinical urine samples during a large-scale radiation incident event. Verification of method performance, as required for clinical laboratory testing, is accomplished by the evaluation of routine, periodic measurements of radioactive spiked samples for quality control, performance testing, and accuracy checks. Radionuclide stability of alpha and beta emitters in urine for LSC analysis is an important consideration. The purpose of this work is to demonstrate optimal preparations and storage conditions of samples used for method verification.

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Authors and Affiliations

  1. Inorganic and Radiation Analytical Toxicology Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Hwy, MS S110-5, 30341-3717, Atlanta, GA, Georgia

    Olga Piraner, Jonathan Button, Cynthia D. Ward & Liza Valentin-Blasini

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  1. Olga Piraner
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  2. Jonathan Button
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  3. Cynthia D. Ward
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  4. Liza Valentin-Blasini
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Correspondence to Olga Piraner.

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Disclaimer The findings and conclusions in this study are those of the authors and do not necessarily represent the views of the U.S. Department of Health and Human Services or the Centers for Disease Control and Prevention. Use of trade names and commercial sources is for identification only and does not constitute endorsement by the U.S. Department of Health and Human Services or the Centers for Disease Control and Prevention.

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Piraner, O., Button, J., Ward, C.D. et al. Investigation of select radionuclides stability in urine under various conditions for liquid scintillation counting (LSC). J Radioanal Nucl Chem 333, 2115–2120 (2024). https://doi.org/10.1007/s10967-024-09433-6

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  • DOI: https://doi.org/10.1007/s10967-024-09433-6

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