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Assessment of 14C-sulfadiazine on Danio rerio (zebrafish)

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Abstract

Antimicrobials, besides application in pharmaceuticals, are used as growth promoters in agriculture, especially for cattle, pigs, and poultry production, as well as, complement for fish in aquaculture. In addition to uses mentioned above, the improper disposal of these substances may cause problems in the aquatic environments such as bioaccumulation, bioconcentration and biomagnification. Thus, the aim of this study was to evaluate the bioconcentration and depuration of sulfadiazine using the teleost fish Danio rerio as test organism. During 20 days of exposal to 14C-sulfadiazine, a small amount of the antimicrobial concentration was observed on fish. Further, no depuration was noted during this period.

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Authors and Affiliations

  1. Ecotoxicology Laboratory, Center for Nuclear Energy in Agriculture, University of Sao Paulo, Av. Centenário, 303, Postal Code: 96, 13416-000, Piracicaba, SP, Brazil

    Aline Trentini Da Silveira, Lucineide Aparecida Maranho, Nádia Hortense Torres & Valdemar Luiz Tornisielo

  2. Federal University of São Carlos (UFSCar), Rodovia João Leme dos Santos, Km 110 - SP-264, 18052-780, Sorocaba, SP, Brazil

    Aline Trentini Da Silveira & Mônica Jones Costa

  3. Post-Graduated Program on Process Engineering, Tiradentes University, Av. Murilo Dantas, 300, Farolândia, 49032-490, Aracaju, SE, Brazil

    Nádia Hortense Torres, Luiz Fernando Romanholo Ferreira & Marilia Moura de Salles Pupo

  4. Institute of Technology and Research, Av. Murilo Dantas, 300, Farolândia, 49032- 490, Aracaju, SE, Brazil

    Nádia Hortense Torres, Luiz Fernando Romanholo Ferreira & Marilia Moura de Salles Pupo

  5. Laboratory for Bioremediation and Metagenomics Research (LBMR), Department of Microbiology (DM), Babasaheb Bhimrao Ambedkar University (A Central University), Vidya Vihar, Raebareli Road, Lucknow, Uttar Pradesh, 226 025, India

    Ram Naresh Bharagava

  6. Department of Environmental Engineering, Federal University of Sergipe, Av. Marechal Rondon, s/n, Jd. Rosa Elze, São Cristóvão, SE, Brazil

    Bruno Santos Souza

Authors
  1. Aline Trentini Da Silveira
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  2. Lucineide Aparecida Maranho
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  9. Valdemar Luiz Tornisielo
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Correspondence to Marilia Moura de Salles Pupo.

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Da Silveira, A.T., Maranho, L.A., Torres, N.H. et al. Assessment of 14C-sulfadiazine on Danio rerio (zebrafish). J Radioanal Nucl Chem 318, 1001–1008 (2018). https://doi.org/10.1007/s10967-018-6058-z

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  • DOI: https://doi.org/10.1007/s10967-018-6058-z

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