Abstract
The aim of the present study is to establish a time and cost effective Na[18F]F preparation method. The process is composed of absorbing radioactive impurities with cation exchange cartridge (CM), trapping 18F-fluroide with QMA cartridges, and formulating the product. The total preparation time determined at the end of bombardment was 4 min and the radiochemical yield was 82 % (n = 29). The final formulated Na[18F]F solution satisfies the USP criteria for quality control.
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Acknowledgments
This study was supported by a grant of the Korea Institute of Radiological and Medical Sciences (KIRAMS), funded by Ministry of Science, ICT and Future Planning, Republic of Korea (1711021927/50530-2015).
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Choi, J.Y., Lee, J.W., Lee, K.C. et al. Time and cost effective production of sodium [18F]fluoride using a dedicated automation module with disposable cassettes for GMP environment. J Radioanal Nucl Chem 309, 983–987 (2016). https://doi.org/10.1007/s10967-016-4709-5
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DOI: https://doi.org/10.1007/s10967-016-4709-5