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A Dual-Signal Sensing for the Visual and Luminescent Detection of p-Phenylenediamine Based on Cerium-Nitrogen-Co-Doped Carbon Dots

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Abstract

Herein, a visual and luminescent dual-mode (colorimetric and fluorometric) method for the detection of P-phenylenediamine (PPD) in hair dye was successfully established based on cerium-nitrogen co-doped carbon dots (Ce, N-CDs) that displayed remarkable luminescence and peroxidase activity. Ce, N-CDs catalyzed H2O2 to produce superoxide anion, which then oxidized the colorless 3,3,5,5-tetramethylbenzidine (TMB) into blue oxidized TMB (oxTMB), capable of quenching the fluorescence through fluorescence resonance energy transfer (FRET) between Ce, N-CDs and oxTMB. The reducing properties of PPD could reduce oxTMB back to TMB, leading to a decrease in the absorption intensity of oxTMB and a fluorescence recovery of Ce, N-CDs. As a result, the quantitative detection of PPD could be achieved by measuring the absorption values of oxTMB and the fluorescence signal of Ce, N-CDs. The detection limits for PPD were calculated as 0.36 µM and 0.10 µM for colorimetry and fluorimetry, respectively. Furthermore, smartphone application (ColorPicker) capable of measuring the RGB value of the color was utilized in the detection system, facilitating on-site quantitative detection. This approach effectively shortens the detection time and simplifies the operation, offering a powerful and convenient tool for real-time monitoring of PPD.

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Funding

This work was supported by the National Natural Science Foundation of China (No. 82073604 and 82304195).

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Authors and Affiliations

  1. Hunan Key Laboratory of Typical Environment Pollution and Health Hazards, University of South China, Hengyang, 421001, People’s Republic of China

    Qianwen Li, Yu Yin, Wenjuan Wang, Bin Liu, Wei Tong, Xu Zhang, Jinquan Liu & Shengyuan Yang

  2. Department of Public Health Laboratory Sciences, School of Public Health, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, People’s Republic of China

    Qianwen Li, Yu Yin, Wenjuan Wang, Bin Liu, Wei Tong, Xu Zhang, Jinquan Liu & Shengyuan Yang

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  1. Qianwen Li
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  2. Yu Yin
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  3. Wenjuan Wang
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  4. Bin Liu
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  5. Wei Tong
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  6. Xu Zhang
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  7. Jinquan Liu
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Contributions

Q. L. Conceptualization, Methodology, Investigation, Writing - review & editing. Y.Y. Methodology. W. W. Writing - review & editing. B. L. Investigation. W. T. Data curation, Investigation. X.Z. Investigation, Validation.J. L. Conceptualization, Supervision, Writing e review & editing, Funding acquisition. S.Y. Supervision, Funding acquisition, Writing e review & editing.

Corresponding authors

Correspondence to Jinquan Liu or Shengyuan Yang.

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Li, Q., Yin, Y., Wang, W. et al. A Dual-Signal Sensing for the Visual and Luminescent Detection of p-Phenylenediamine Based on Cerium-Nitrogen-Co-Doped Carbon Dots. J Fluoresc (2024). https://doi.org/10.1007/s10895-024-03696-8

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