Skip to main content
SpringerLink
Log in

Complement Study Versus CINH Gene Testing for the Diagnosis of Type I Hereditary Angioedema in Children

  • Letter to Editor
  • Published:
Journal of Clinical Immunology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Caballero T, Baeza ML, Cabañas R, et al. Consensus statement on the diagnosis, management, and treatment of angioedema mediated by bradykinin. Part I. Classification, epidemiology, pathophysiology, genetics, clinical symptoms, and diagnosis. J Investig Allergol Clin Immunol. 2011;21(5):333–347; quiz follow 347.

  2. Craig TJ, Aygören-Pürsün E, Bork K, et al. WAO guideline for the management of hereditary angioedema. World Allergy Organ J. 2012;5(12):182–99. doi:10.1097/WOX.0b013e318279affa.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Nielsen EW, Johansen HT, Holt J, Mollnes TE. C1 inhibitor and diagnosis of hereditary angioedema in newborns. Pediatr Res. 1994;35(2):184–7. doi:10.1203/00006450-199402000-00012.

    Article  PubMed  CAS  Google Scholar 

  4. Grumach AS, Ceccon ME, Rutz R, Fertig A, Kirschfink M. Complement profile in neonates of different gestational ages. Scan J Immunol. 2014;79(4):276–81. doi:10.1111/sji.12154.

    Article  CAS  Google Scholar 

  5. Roche O, Blanch A, Duponchel C, et al. Hereditary angioedema: the mutation spectrum of SERPING1/C1NH in a large spanish cohort. Hum Mutat. 2005;26(2):135–44. doi:10.1002/humu.20197.

    Article  PubMed  CAS  Google Scholar 

  6. López-Lera A, Garrido S, Roche O, López-Trascasa M. SERPING1 mutations in 59 families with hereditary angioedema. Mol Immunol. 2011;49(1–2):18–27. doi:10.1016/j.molimm.2011.07.010.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Allergy, Hospital La Paz Institute for Health Research (IdiPAZ), P. Castellana, 261, 28046, Madrid, Spain

    María Pedrosa, Elsa Phillips-Angles & Teresa Caballero

  2. Department of Immunology, Hospital La Paz Institute for Health Research (IdiPAZ), Madrid, Spain

    Alberto López-Lera & Margarita López-Trascasa

  3. Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER) U754, Madrid, Spain

    Alberto López-Lera, Margarita López-Trascasa & Teresa Caballero

Authors
  1. María Pedrosa
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Elsa Phillips-Angles
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Alberto López-Lera
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Margarita López-Trascasa
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Teresa Caballero
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to María Pedrosa.

Ethics declarations

Conflict of Interest

Dr. María Pedrosa has received speaker fees from Shire, sponsorship for educational purposes and has taken part in clinical trials sponsored by Jerini AG/Shire, CSL-Behring, and Pharming NV.

Dr. Elsa Phillips-Angles has received sponsorship for educational purposes and has taken part in clinical trials sponsored by Shire and CSL-Behring.

Dr. Alberto López-Lera has received sponsorship for educational purposes sponsored by Jerini AG/Shire.

Dr. Margarita López Trascasa has received sponsorship for educational purposes sponsored by Jerini AG/Shire.

Dr. Teresa Caballero has received speaker fees from Shire and ViroPharma, consultancy fees from CSL Behring, Shire, SOBI and ViroPharma, and funding for travel and meeting attendance from CSL Behring and Shire; and has participated in clinical trials or registries for CSL Behring, Dyax, Pharming, Shire and ViroPharma.

Funding

This study was funded by a grant awarded by the Spanish Ministry of Health (SAF 2012/38636)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Pedrosa, M., Phillips-Angles, E., López-Lera, A. et al. Complement Study Versus CINH Gene Testing for the Diagnosis of Type I Hereditary Angioedema in Children. J Clin Immunol 36, 16–18 (2016). https://doi.org/10.1007/s10875-015-0222-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10875-015-0222-9

Keywords

Search

Navigation