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Ascorbic acid sensing utilizing graphene oxide based on UV–Visible bathochromic shift

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Abstract

This study introduces a novel technique for detecting ascorbic acid (AA) using graphene oxide (GO). As a vital compound in nutrition and healthcare, precise sensing is imperative. Our approach leverages GO's unique properties, capitalizing on its interactions with AA as a reducing agent to establish a robust sensing platform. The UV–Visible spectra of GO revealed distinct absorption peak shifts corresponding to varying AA concentrations. This shift, directly proportional to AA concentration, offers a quantifiable parameter for precise sensing. The observed shift is attributed to AA-induced reduction of GO, restoring π-conjugation within the graphene structure. The US Department of Health and Human Services specifies that the vitamin C amount in our body ranges from 300 mg to 2 ( National Institutes of Health (NIH) Office of Dietary Supplements (ODS) US Department of Health and Human Services, Vitamin C Fact Sheet for Health Professionals, https://ods.od.nih.gov/factsheets/VitaminC-HealthProfessional/), which falls within the sensing range achieved using UV–Visible spectroscopy. The method prioritizes achieving sensitivity within the specific range, negating the need for excessively high sensitivity. In summary, our innovative GO-based approach provides a suitable method for ascorbic acid sensing with wide-ranging applications in clinical diagnostics, food quality control, and environmental monitoring.

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Acknowledgements

This work was supported by the Kerala State Council for Science, Technology & Environment—SRS Project 107/2016. Both authors thank the Central Sophisticated Instrumentation Facility (CSIF), University of Calicut, Kerala, for providing FESEM facilities. The authors would also like to thank FIST2 (DST, Government of India) for providing the X-ray diffraction facility and UGC-SAP for the micro Raman facility in the Department of Physics, University of Calicut.

Funding

This work was supported by the Kerala State Council for Science, Technology and Environment-SRS Project 107/2016. The authors would also like to thank UGCSAP and FIST2 (DST, Government of India) for providing the research facilities in the Department of Physics, University of Calicut.

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Authors and Affiliations

  1. Laboratory for Mesoscopic Sciences and Devices, Department of Physics, University of Calicut, Kerala, 673635, India

    Aruna Unnikrishnan, V. Megha & Libu K. Alexander

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  1. Aruna Unnikrishnan
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  2. V. Megha
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  3. Libu K. Alexander
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Contributions

Aruna Unnikrishnan contributed towards conceptualization; data curation; investigation; methodology; validation; visualization; formal analysis; and roles/ writing—original draft. Megha V contributed to the formal analysis. Libu K. Alexander contributed towards conceptualization; funding acquisition; supervision; methodology; validation; and writing—review and editing.

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Correspondence to Aruna Unnikrishnan.

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Unnikrishnan, A., Megha, V. & Alexander, L.K. Ascorbic acid sensing utilizing graphene oxide based on UV–Visible bathochromic shift. J Mater Sci: Mater Electron 35, 904 (2024). https://doi.org/10.1007/s10854-024-12672-8

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