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A guided walk through Larry Hench’s monumental discoveries

  • In Honor of Larry Hench
  • Published:
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Abstract

Here we review and summarize the groundbreaking scientific researches of the late Professor Larry L. Hench, including several of his key discoveries in materials science and engineering. First, we provide a statistical overview of his exceptional scientific performance using Scopus, Web of Science, and other Web sites to extract statistical data on his scientific publications and patents. Professor Hench achieved an exceptionally high h-index of 77 (Scopus) for the field of materials science and engineering, which resulted from his 340 research papers, 210 conference papers, 41 patents, 24 books, 4 editorial notes, and 3 biographies starting in 1967. Then, we summarize and highlight his seminal articles, books, and patents in several research areas, such as bioactive glasses, optical gel glasses, biocomposites/coatings, glass–ceramics, biophotonics, advanced ceramics, semiconducting and ionic conducting glasses, glass corrosion, and nuclear waste disposal. Prof. Hench not only discovered the first man-made material to form a chemical bond with bone and initiated a whole new field—bioactive glasses and glass–ceramics—but also made several other important scientific discoveries. It is quite clear that he was one of the most influential materials scientists/engineers of all time! We hope that this review is not only useful for all persons interested in materials science and engineering but also encourages students and younger investigators to make use of this accumulated knowledge to design novel materials and discover new applications for glasses and ceramics.

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Modified from Ref. [40], with permission from Springer

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Reproduced from Ref. [269], with permission from Elsevier

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  122. West JK, Latour R, Hench LL (1997) Molecular modeling study of adsorption of poly-l-lysine onto silica glass. J Biomed Mater Res 37(4):585–591

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  123. Thompson ID, Hench LL (1998) Mechanical properties of bioactive glasses, glass-ceramics and composites. Proc Inst Mech Eng Part H J Eng Med 212(H2):127–136

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  124. Hench LL, Wheeler DL, Greenspan DC (1998) Molecular control of bioactivity in sol–gel glasses. J Sol-Gel Sci Technol 13(1–3):245–250

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  126. Lobel KD, Hench LL (1998) In vitro adsorption and activity of enzymes on reaction layers of bioactive glass substrates. J Biomed Mater Res 39(4):575–579

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  319. Hench LL, Simmons JH, Zhu B, Ochoa R (1993) Laser dye impregnated silica sol–gel monoliths—provides high casing efficiency and improved photochemical stability, US5222092-A

  320. Ochoa R, Zhu B, Hench LL, Simmons JH (1994) Photochemically stable dye laser prodn.—by impregnating porous silica gel–sol monolith with laser dye soln. then drying, US5356667-A

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  428. Fenn MB, Xanthopoulos P, Pyrgiotakis G, Grobmyer SR, Pardalos PM, Hench LL (2011) Raman spectroscopy for clinical oncology. Adv Opt Technol. Article ID 213783. doi:10.1155/2011/213783

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  457. Hench LL, Karakoti A, Krishna MSB, Reid D, Seal S, Krishna MSB, Hench L, Krishna MS, Read D, Sil S, Reyd D, Moorthy SBH (2009–2015) Manufacture of functionalized aluminosilicate powder for producing structural material, involves functionalizing aluminosilicate powder with liquid reagent and drying powder, WO2009082442-A1; AU2008341102-A1; EP2222611-A1; CA2712575-A1; CN101977868-A; US2011112272-A1; MX2010006298-A1; KR2011069743-A; JP2011523392-W; IN201002042-P2; RU2010130262-A; HK1153998-A0; RU2485065-C2; SG162859-A1; SG162859-B; AU2008341102-B2; IL205996-A; JP5749931-B2; BR200822065-A2; JP2015143191-A

  458. Seal S, Reid DL, Hench LL (2012) Composition used for scavenging oil from oil–water mixture, comprises functionalized fly ash particles that include bulk portion having functionalized surfaces with reactive groups/materials having hydrophobic groups covalently bound to it, US2012006753-A1; US8318625-B2

  459. Seal S, Reid DL, Hench LL (2013) Forming functionalized fly ash particles useful e.g. for scavenging oil from oil–water mixture, comprises contacting fly ash particles with hydroxide compound, and reacting the obtained fly ash particles with organic alcohol or organic acid, US2013040803-A1; US8404609-B2

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Acknowledgements

The authors are grateful to the São Paulo Research Foundation—FAPESP, # 2013/07793-6—for the financial support of this work and for granting a postdoctoral fellowship to Maziar Montazerian (# 2015/13314-9).

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  1. Department of Materials Engineering (DEMa), Center for Research, Technology and Education in Vitreous Materials (CeRTEV), Federal University of São Carlos (UFSCar), São Carlos, SP, 13.565-905, Brazil

    Maziar Montazerian & Edgar D. Zanotto

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Correspondence to Maziar Montazerian or Edgar D. Zanotto.

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Montazerian, M., Zanotto, E.D. A guided walk through Larry Hench’s monumental discoveries. J Mater Sci 52, 8695–8732 (2017). https://doi.org/10.1007/s10853-017-0804-4

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