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A synopsis of the 2021 International Society of Fertility Preservation bi-annual meeting

  • Fertility Preservation
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Abstract

On November 19, 2021, the first virtual meeting of the International Society for Fertility Preservation (ISFP) took place. Eight experts in the field of reproductive medicine presented important updates on their research in the field of fertility preservation and reproductive surgery for absolute uterine factor infertility. Presentations included talks on ovarian stem cell therapy for premature ovarian insufficiency, practical aspects of oocyte vitrification, ovarian stimulation for patients with breast cancer, in vitro maturation of oocytes at the time of ovarian tissue harvesting, male fertility preservation, and uterine transplantation. These presentations are summarized below and can be viewed in their entirety at www.isfp-fertility.org

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References

  1. Herraiz S, Buigues A, Díaz-García C, Romeu M, Martínez S, Gómez-Seguí I, Simón C, Hsueh AJ, Pellicer A. Fertility rescue and ovarian follicle growth promotion by bone marrow stem cell infusion. Fertil Steril. 2018;109(5):908-918.e2.

    Article  Google Scholar 

  2. Buigues A, Marchante M, de Miguel-Gómez L, Martinez J, Cervelló I, Pellicer A, Herraiz S. Stem cell-secreted factor therapy regenerates the ovarian niche and rescues follicles. Am J Obstet Gynecol. 2021;225(1):65.e1-65.e14.

    Article  CAS  Google Scholar 

  3. Sathananthan AH, Trounson AO. Mitochondrial morphology during preimplantational human embryogenesis. Hum Reprod. 2000;15(Suppl 2):148–59.

    Article  Google Scholar 

  4. Shanmughapriya S, Langford D, Natarajaseenivasan K. Inter and Intracellular mitochondrial trafficking in health and disease. Ageing Res Rev. 2020;62:101128.

    Article  CAS  Google Scholar 

  5. Zhang J, Liu H, Luo S, Lu Z, Chávez-Badiola A, Liu Z, Yang M, Merhi Z, Silber SJ, Munné S, Konstantinidis M, Wells D, Tang JJ, Huang T. Live birth derived from oocyte spindle transfer to prevent mitochondrial disease. Reprod Biomed Online. 2017;34(4):361–8.

    Article  Google Scholar 

  6. Cobo A, García-Velasco JA, Coello A, Domingo J, Pellicer A, Remohí J. Oocyte vitrification as an efficient option for elective fertility preservation. Fertil Steril. 2016;105(3):755-764.e8.

    Article  Google Scholar 

  7. Coello A, Sanchez E, Vallejo B, Meseguer M, Remohí J, Cobo A. Effect of oocyte morphology on post-warming survival and embryo development in vitrified autologous oocytes. Reprod Biomed Online. 2019;38(3):313–20.

    Article  Google Scholar 

  8. Chien A, Chambers J, McCauley F, et al. Fertility preservation with ovarian stimulation and time to treatment in women with stage II-III breast cancer receiving neoadjuvant therapy. Breast Cancer Res Treat. 2017;165(1):151–9.

    Article  Google Scholar 

  9. Quinn M, Cakmak H, Letourneau J, et al. Response to ovarian stimulation is not impacted by breast cancer diagnosis. Human Reprod. 2017;32(3):568–74.

    CAS  Google Scholar 

  10. Letourneau J, Juarez-Hernandez F, Wald K, et al. Concomitant tamoxifen or letrozole for optimal oocyte yield during fertility preservation for breast cancer: the Tamoxifen or Letrozole in Estrogen Sensitive tumors (TALES) randomized clinical trial. J Assist Reprod Genet. 2021;38(9):2455–63.

    Article  Google Scholar 

  11. Greer A, Lanes A, Poorvu P, et al. The impact of fertility preservationon the timing of breast cancer treatment, recurrence and survival. Cancer. 2021;127(20):3872–80.

    Article  Google Scholar 

  12. Turan V, Bedoschi G, Moy F, et al. Safety and feasibility of performing two consecutive ovarian stimulation cycles with the use of letrozole-gonadotropin protocol for fertility preservation in breast cancer patients. Fertil Steril. 2013;100(6):1681–5.

    Article  CAS  Google Scholar 

  13. Nikiforov D, Junping C, Cadenas J, Shukla V, Blanshard R, Pors SE, Kristensen SG, Macklon KT, Colmorn L, Ernst E, Bay-Bjørn AM, Ghezelayagh Z, Wakimoto Y, Grøndahl ML, Hoffmann E, Andersen CY. Improving the maturation rate of human oocytes collected ex vivo during the cryopreservation of ovarian tissue. J Assist Reprod Genet. 2020;37(4):891–904.

    Article  Google Scholar 

  14. Cadenas J, Nikiforov D, Pors SE, Zuniga LA, Wakimoto Y, Ghezelayagh Z, Mamsen LS, Kristensen SG, Andersen CY. A threshold concentration of FSH is needed during IVM of ex vivo collected human oocytes. J Assist Reprod Genet. 2021;38(6):1341–8.

    Article  Google Scholar 

  15. Dolmans MM, von Wolff M, Poirot C, Diaz-Garcia C, Cacciottola L, Boissel N, Liebenthron J, Pellicer A, Donnez J, Andersen CY. Transplantation of cryopreserved ovarian tissue in a series of 285 women: a review of five leading European centers. Fertil Steril. 2021;115(5):1102–15.

    Article  CAS  Google Scholar 

  16. Poirot C, Fortin A, Dhedin N, Brice P, Socie G, Lacorte JM, et al. Post-transplant outcome of ovarian tissue cryopreserved after chemotherapy in hematologic malignancies. Haematologica. 2019;104:e360–3.

    Article  CAS  Google Scholar 

  17. Shapira M, Dolmans MM, Silber S, Meirow D. Evaluation of ovarian tissue transplantation: results from three clinical centers. Fertil Steril. 2020;114:388–97.

    Article  Google Scholar 

  18. Meistrich M. Effects of chemotherapy and radiotherapy on spermatogenesis in humans. Fertil Steril. 2013;100:1180–6.

    Article  CAS  Google Scholar 

  19. Kohler TS, Kondapalli LA, Shah A, et al. Results of the survey for preservation of adolescent reproduction (SPARE) study; gender disparity in delivery of fertility preservation message to adolescents with cancer. J Assist Reprod Genet. 2011;28(3):269–77.

    Article  Google Scholar 

  20. Sheth KR, Sharma V, Helfand BT, et al. Improved fertility preservation care for male patients with cancer after establishment of formalized oncofertility program. J Urol. 2012;187:979–86.

    Article  Google Scholar 

  21. Brinster R. Male germline cells: from mice to men. Science. 2007;316(5823):404–5.

    Article  CAS  Google Scholar 

  22. Molne J, Broeker V, Ekberg J, et al. Monitoring of human uterus transplantation with cervical biopsies: a provisional scoring system for rejection. Am J Transplant. 2017;17(6):1628–36.

    Article  CAS  Google Scholar 

  23. Brannstrom M, Johanneson L, Dahm-Kahler P, et al. First clinical uterus transplantation trial: a six-month report. Fertil Steril. 2014;10(5):1228–36.

    Article  Google Scholar 

  24. Flyckt R, Falcone T, Quintini C, Perni U, Eghtesad B, Richards EG, Farrell RM, Hashimoto K, Miller C, Ricci S, Ferrando CA, D’Amico G, Maikhor S, Priebe D, Chiesa-Vottero A, Heerema-McKenney A, Mawhorter S, Feldman MK, Tzakis A. First birth from a deceased donor uterus in the United States: from severe graft rejection to successful cesarean delivery. Am J Obstet Gynecol. 2020;223(2):143–51.

    Article  CAS  Google Scholar 

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Funding

The study was supported by the Fonds National de la recherche Scientifique de Belgique (F.R.S.-FNRS/FRIA FC29657 awarded to L. Cacciottola, FNRS-PDR Convention T.0077.14, Excellence of Science FNRS–EOS number 30443682, and grant 5/4/150/5 awarded to M.-M. Dolmans), Fonds Spéciaux de Recherche, Fondation St Luc and the Foundation Against Cancer, and donations from the Ferrero family.

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Authors and Affiliations

  1. Gynecology Research Unit, Institut de Recherche Expérimentale Et Clinique, Université Catholique de Louvain, Brussels, Belgium

    Luciana Cacciottola

  2. Department of Gynecology, Cliniques Universitaires Saint-Luc, Brussels, Belgium

    Marie-Madeleine Dolmans

  3. Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Medical College of Cornell University, New York, NY, USA

    Glenn L. Schattman

Authors
  1. Luciana Cacciottola
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  2. Marie-Madeleine Dolmans
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  3. Glenn L. Schattman
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Correspondence to Glenn L. Schattman.

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Cacciottola, L., Dolmans, MM. & Schattman, G.L. A synopsis of the 2021 International Society of Fertility Preservation bi-annual meeting. J Assist Reprod Genet 39, 1727–1732 (2022). https://doi.org/10.1007/s10815-022-02568-z

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  • DOI: https://doi.org/10.1007/s10815-022-02568-z

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