Abstract
Background
Femtosecond laser-assisted in situ keratomileusis (FS-LASIK) with accelerated corneal crosslinking (FS-LASIK Xtra) is a recent procedure to achieve safer corneal ablation in myopic patients with borderline corneal thickness. Despite its well-accepted effectiveness, the development of remarkable interface haze is a potential concern but has rarely been reported and discussed.
Methods
We report for the first time a case series of 11 eyes of 7 patients who developed typical interface haze 1–3 months after FS-LASIK Xtra for the correction of myopia with astigmatism, with intensity grades ranging from 0.5 + to 3 + at the time of onset.
Results
The preclinical spherical diopters of the 7 patients ranged from − 2.25 D to − 9.25 D and cylindrical diopters ranged from − 0.25 D to − 2.50 D. The haze tended to be self-limiting, and topical anti-inflammatory therapy was given to moderate and severe cases, who responded well to treatment.
Conclusions
The development of clinically significant interface haze is a relatively rare complication after FS-LASIK Xtra but tends to have a higher incidence and intensity compared to conventional stromal surgery such as FS-LASIK. Timely treatment and close follow-up are essential to patients undertaking FS-LASIK Xtra.
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Funding
This work was supported by the Science & Technology Department of Sichuan Province (China) funding project (No. 2021YFS0221, No.2023YFS0179), 1.3.5 project for disciplines of excellence, West China Hospital, Sichuan University (No.2022HXFH032, ZYJC21058, 2021-023, 2022-014), and the Postdoctoral Research Funding of West China Hospital (No. 2020HXBH044).
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All authors conducted clinical observation and the literature search. LW wrote the manuscript. HY the surgery and provided supervision. HY and KM revised the manuscript
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Yin, H., Wang, L., Gong, R. et al. Development of interface haze after femtosecond laser-assisted in situ keratomileusis with accelerated corneal crosslinking: a case series. Int Ophthalmol 43, 4333–4342 (2023). https://doi.org/10.1007/s10792-023-02800-4
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DOI: https://doi.org/10.1007/s10792-023-02800-4