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Ocular pulse amplitude and visual field changes in patients diagnosed with aortic regurgitation

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Abstract

Purpose

To examine whether there is a relationship between ocular pulse amplitude (OPA), intraocular pressure (IOP), and visual field (VF) deterioration among the patients diagnosed with aortic regurgitation (AR).

Methods

Twenty-nine patients (average age of 62.06 ± 13.27 years) with AR diagnosis without glaucoma history as AR group and 32 healthy participants (average age 63.81 ± 6.42 years) as control group were included in the study. Routine ophthalmologic examination including VF test [mean deviation (MD), pattern standard deviation (PSD) and VF index (VFI) values were recorded], diurnal IOP and OPA measurements with Pascal dynamic contour tonometry (DCT) was conducted on the patients. VF deficits were classified by Glaucoma Staging System 2 (GSS 2) score.

Results

Sixteen (50.0%) of 32 healthy subjects and 14 (48.3%) of 29 AR patients were female (p = 1.000). The measurement conducted at 15:30 among the diurnal IOP measurements performed with the Pascal DCT was found to be statistically significantly higher in the AR group (p = 0.009). While the MD and PSD values of the group diagnosed with AR were determined to be statistically significantly high, the VFI value was found to be significantly low. When the healthy cases and the patients diagnosed with AR were compared, it was observed that there was a statistically significant positive correlation in terms of the significant GSS 2 stage (p < 0.001).

Conclusion

Although there was no significant increase in IOP, VF deficits were detected in patients with AR. These VF pathologies may be due to the ocular perfusion disorder in AR. However, additional comprehensive studies that also examine perfusion are needed to further confirm this.

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Acknowledgements

I would like to thank Mr. Ufuk Bilki for his language editorial support.

Funding

The authors obtained no commercial provider for the investigation, authorship, and broadcasting of the study.

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Authors and Affiliations

  1. Department of Ophthalmology, University of Health Sciences Dr. Behcet Uz Child Diseases and Surgery Research and Training Hospital, Izmir, Turkey

    Sinan Bekmez & Erdem Eris

  2. Department of Ophthalmology, Faculty of Medicine, Adnan Menderes University, Aydin, Turkey

    Harun Cakmak & Tolga Kocaturk

  3. Department of Cardiology, Faculty of Medicine, Adnan Menderes University, Aydin, Turkey

    Cagdas Akgullu & Ufuk Eryilmaz

Authors
  1. Sinan Bekmez
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  2. Harun Cakmak
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  3. Cagdas Akgullu
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  4. Tolga Kocaturk
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  5. Erdem Eris
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  6. Ufuk Eryilmaz
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Contributions

SB, HC, CA: designed the research; SB, TK, UE: were involved in patient care; SB, CA, UE: collected the data; SB, HC, CA, EE: analysis and interpretation of data; SB, EE: drafting the manuscript; SB, EE, UE: design of the work, revising the work critically for important intellectual content; All authors approved the final version of manuscript.

Corresponding author

Correspondence to Erdem Eris.

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Conflicts of interest

The authors stated no possible conflicts of interest to the investigation, authorship, and broadcasting of the study.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This study was approved by the institutional Board Review of the University of Adnan Menderes (Protocol Number 2012/120).

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Informed consent was obtained from all individual participants included in the study.

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It was obtained from all individual participants included in the study.

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Bekmez, S., Cakmak, H., Akgullu, C. et al. Ocular pulse amplitude and visual field changes in patients diagnosed with aortic regurgitation. Int Ophthalmol 43, 859–866 (2023). https://doi.org/10.1007/s10792-022-02488-y

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  • DOI: https://doi.org/10.1007/s10792-022-02488-y

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