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Comparison of densitometric profile after deep lamellar keratoplasty with two different techniques for treatment of keratoconus

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Abstract

Purpose

To compare densitometric outcome of two techniques of deep lamellar keratoplasty using Pentacam HR corneal densitometry software.

Methods

Postoperative outcomes of 31 patients with big bubble (BB) and 28 patients with Melles (M) surgery for the treatment of keratoconus were evaluated. Data were gathered at least 3 months after the removal of all sutures including demographic data, uncorrected distance visual acuity (UCDVA), best spectacle-corrected visual acuity (BSCVA), refraction and endothelial cell count. Moreover, the Scheimpflug images were taken by Pentacam® HR to assess keratometric profile, densitometric outcomes in different depths and zones of the cornea and central corneal thickness. Anterior segment OCT was performed in ten cases of M group.

Results

Thirty-one eyes with BB and 27 eyes M surgery were enrolled. Comparison of densitometric profile between groups revealed no statistical significance in zone 0–2 mm, zone 2–6 mm and zone 10–12 mm in all depths (all P values >  0.05). Zone 6–10 mm of M group had lower densitometric readings (more transparent) in anterior, central and posterior layers of the cornea in comparison with BB group (all P <  0.05). Also no statistical difference was found in UCDVA, BSCVA, spherical or cylindrical refractive error, and spherical equivalent, keratometric readings, endothelial cell count and central corneal thickness in two groups (all P values >  0.05).

Conclusion

Densitometric profiles were identical in both methods in visually important zones so as visual and refractive outcomes.

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Author information

Authors and Affiliations

  1. Department of Ophthalmology, Isfahan University of Medical Sciences, Isfahan, Iran

    Mohammad Ghoreishi

  2. Parsian Vision Science Research Institute, Mir St., Isfahan, Iran

    Mohammad Ghoreishi, Abolfazl Kashfi, Mohammadreza Peyman, Shahriar Hanjani & Mohaddese Mohammadinia

  3. Legacy Devers Eye Institute, Portland, USA

    Mike Straiko

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  1. Mohammad Ghoreishi
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  2. Abolfazl Kashfi
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  3. Mohammadreza Peyman
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  4. Shahriar Hanjani
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  5. Mohaddese Mohammadinia
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Correspondence to Abolfazl Kashfi.

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All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership or other equity interest; and expert testimony or patent-licensing arrangements) or nonfinancial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Ghoreishi, M., Kashfi, A., Peyman, M. et al. Comparison of densitometric profile after deep lamellar keratoplasty with two different techniques for treatment of keratoconus. Int Ophthalmol 39, 1105–1113 (2019). https://doi.org/10.1007/s10792-018-0921-3

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  • DOI: https://doi.org/10.1007/s10792-018-0921-3

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