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S(+)-ibuprofen (dexibuprofen) — Excellent tolerance has not to be combined with poor clinical efficacy

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Abstract

S(+)-ibuprofen (dexibuprofen) is an NSAID offering a lot of advantages in the treatment of rheumatism and pain. A randomized double-blind, parallel group study in 110 patients showed equivalence in efficacy of 900 mg dexibuprofen (Seractil 300 mg, Gebro Fieberbrunn, Austria) vs. 150 mg diclofenac sodium. Regarding tolerance there was a trend to superiority of dexibuprofen. Therefore dexibuprofen can be characterized as an effective and very tolerable drug against inflammation and pain.

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Authors and Affiliations

  1. Gebro Broschek GmbH, A-6391, Fieberbrunn

    A. Zohmann & G. Lötsch

  2. Rehabilitation Centre for Diseases of Rheumatic Origin, A-5630, Bad Hofgastein

    R. Hawel

  3. Rehabilitation Centre for Rheumatic Diseases and Cardiovascular Diseases, A-5760, Saalfelden

    G. Klein

  4. Ludwig Boltzmann Institute for Rehabilitation of Internal Diseases, A-5760, Saalfelden, Austria

    G. Klein & W. Kullich

Authors
  1. A. Zohmann
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  2. R. Hawel
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  3. G. Klein
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  4. W. Kullich
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  5. G. Lötsch
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Zohmann, A., Hawel, R., Klein, G. et al. S(+)-ibuprofen (dexibuprofen) — Excellent tolerance has not to be combined with poor clinical efficacy. Inflammopharmacol 6, 75–79 (1998). https://doi.org/10.1007/s10787-998-0008-2

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  • DOI: https://doi.org/10.1007/s10787-998-0008-2

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