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Prevalence of Suspected Diastolic Dysfunction in Patients with a Clinical Diagnosis of Congestive Heart Failure

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Abstract

Introduction: The prevalence of diastolic left ventricular (LV) dysfunction in a population presenting with a suspected diagnosis of congestive heart failure (CHF) is questionable and widely variable in the current literature. To minimize the disparity, we evaluated a large echocardiographic database to investigate the prevalence of systolic and suspected diastolic LV dysfunction in those with a suspected clinical diagnosis of CHF.

Methods: We retrospectively reviewed echocardiograms performed at our institution and evaluated the prevalence of abnormal LV systolic and diastolic function in those with a suspected clinical diagnosis of CHF. Diastolic dysfunction was defined as the presence of left atrial enlargement, left ventricular hypertrophy and reverse trans-mitral inflow ratio (E/A reversal).

Results: Of the 636 echocardiograms with CHF as the primary diagnosis, 461 had measured LV function. Normal LV systolic function were found in 238 of the patients (48%). Isolated diastolic LV dysfunction was found in 166 patients (36%). Twelve percent of the patients with a suspected clinical diagnosis of CHF had normal LV systolic and diastolic function.

Conclusion: Normal LV systolic function was seen in nearly one-half of the echocardiograms with a suspected clinical diagnosis of CHF. Suspected LV diastolic dysfunction was observed in one-third of the echocardiograms with a suspected clinical diagnosis of CHF.

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References

  1. Zile MR, Brutsaert DL. New concepts in diastolic dysfunction and diastolic heart failure: Part II: causal mechanisms and treatment. Circulation 2002;105(12):1503–1508.

    Article  PubMed  Google Scholar 

  2. Zile MR, Brutsaert DL. New concepts in diastolic dysfunction and diastolic heart failure: Part I: diagnosis, prognosis, and measurements of diastolic function. Circulation 2002;105(11):1387–1393.

    Article  PubMed  Google Scholar 

  3. Aurigemma GP, Gaasch WH. Clinical practice. Diastolic heart failure. N Engl J Med 2004;351(11):1097–1095.

    Article  CAS  PubMed  Google Scholar 

  4. Topol EJ, Traill TA, Fortuin NJ. Hypertensive hypertrophic cardiomyopathy of the elderly. N Engl J Med 1985; 312(5):277–283.

    CAS  PubMed  Google Scholar 

  5. Gaasch WH. Diagnosis and treatment of heart failure based on left ventricular systolic or diastolic dysfunction. Jama 1994;271(16):1276–1280.

    Article  CAS  PubMed  Google Scholar 

  6. Elesber AA, Redfield MM. Approach to patients with heart failure and normal ejection fraction. Mayo Clin Proc 2001;76(10):1047–1052.

    CAS  PubMed  Google Scholar 

  7. Vasan RS, Benjamin EJ, Levy D. Prevalence, clinical features and prognosis of diastolic heart failure: an epidemiologic perspective. J Am Coll Cardiol 1995;26(7):1565–1574.

    Article  CAS  PubMed  Google Scholar 

  8. Redfield MM, Jacobsen SJ, Burnett JC, Jr., Mahoney DW, Bailey KR, Rodeheffer RJ. Burden of systolic and diastolic ventricular dysfunction in the community: appreciating the scope of the heart failure epidemic. Jama 2003; 289(2):194–202.

    Article  PubMed  Google Scholar 

  9. Vasan RS, Larson MG, Benjamin EJ, Evans JC, Reiss CK, Levy D. Congestive heart failure in subjects with normal versus reduced left ventricular ejection fraction: prevalence and mortality in a population-based cohort. J Am Coll Cardiol 1999;33(7):1948–1955.

    Article  CAS  PubMed  Google Scholar 

  10. Gottdiener JS, McClelland RL, Marshall R, et al., Outcome of congestive heart failure in elderly persons: influence of left ventricular systolic function. The Cardiovascular Health Study. Ann Intern Med 2002;137(8):631–639.

    PubMed  Google Scholar 

  11. Banerjee P, Banerjee T, Khand A, Clark AL, Cleland JG. Diastolic heart failure: neglected or misdiagnosed? J Am Coll Cardiol 2002;39(1):138–1341.

    Article  PubMed  Google Scholar 

  12. Hogg K, Swedberg K, McMurray J. Heart failure with preserved left ventricular systolic function; epidemiology, clinical characteristics, and prognosis. J Am Coll Cardiol 2004;43(3):317–327.

    Article  PubMed  Google Scholar 

  13. Masoudi FA, Havranek EP, Smith G, et al., Gender, age, and heart failure with preserved left ventricular systolic function. J Am Coll Cardiol 2003;41(2):217–223.

    Article  PubMed  Google Scholar 

  14. Senni M, Redfield MM. Heart failure with preserved systolic function. A different natural history? J Am Coll Cardiol 2001;38(5):1277–1282.

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Mohammad-Reza Movahed MD, PhD.

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Movahed, MR., Ahmadi-Kashani, M. & Saito, Y. Prevalence of Suspected Diastolic Dysfunction in Patients with a Clinical Diagnosis of Congestive Heart Failure. Heart Fail Rev 10, 263–264 (2005). https://doi.org/10.1007/s10741-005-7539-z

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