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New Flavonoids of the Genus Scutellaria. II. Baicalein and Wogonin Glycosides from S. baicalensis

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Chemistry of Natural Compounds Aims and scope

New glycosides of baicalein (1–4) and wogonin (5 and 6) were found by studying phenolic compounds from roots of Scutellaria baicalensis Georgi (Lamiaceae) grown with treatment by 24-epibrassinolide. The new compounds were baicalein 7-O-(2′′-O-β-D-glucosyl)-β-D-glucuronopyranoside (scutellariside III, 1), baicalein 6-O-β-D-glucopyranoside-7-O-(2′′-O-β-D-glucosyl)-β-D-glucoronopyranoside (scutellariside IV, 2), baicalein 6-O-β-D-glycopyranosyl-7-O-β-D-glucuronopyranoside (scutellariside V, 3), baicalein 7-O-(2′′-O-malonyl)-β-D-glucuronopyranoside (scutellariside VI, 4), wogonin 7-O-(2′′-O-β-D-glucosyl)-β-D-glucuronopyranoside (scutellariside VII, 5), and wogonin 7-O-(2′′-O-malonyl)-β-D-glucuronopyranoside (scutellariside VIII, 5) according to UV and NMR spectroscopic and mass spectrometric data.

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Acknowledgment

The research was supported by the Ministry of Science and Higher Education of the Russian Federation in the framework of Science Projects Nos. 121030100227-7 and FSRG-2023-0027.

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Correspondence to D. N. Olennikov.

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Translated from Khimiya Prirodnykh Soedinenii, No. 2, March–April, 2024, pp. 202–206.

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Olennikov, D.N., Chirikova, N.K. New Flavonoids of the Genus Scutellaria. II. Baicalein and Wogonin Glycosides from S. baicalensis. Chem Nat Compd 60, 229–234 (2024). https://doi.org/10.1007/s10600-024-04294-7

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  • DOI: https://doi.org/10.1007/s10600-024-04294-7

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