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Two New Sesquiterpenoid Glycosides from Rhizomes of Atractylodes lancea

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Chemistry of Natural Compounds Aims and scope

Two new sesquiterpenoid glycosides, (1S,4S,5R,7R)-4,11,14-trihydroxy-guaia-9-en-3-one-11-O-β-Dglucopyranoside (1) and 1β,5α,7α-H-3β,4α,11,14-tetrahydroxyl-guaia-9-en-11-O-D-glucopyranoside (2), were isolated from the water-soluble portion of the ethanolic extract of Atractylodes lancea rhizomes. Their structures were elucidated on the basis of extensive spectroscopic data and application of the CD technique. Compounds 1 and 2 were evaluated for their anti-inflammatory activity by determining their inhibitory activity on lipopolysaccharide-induced nitric oxide production, but both were inactive.

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Acknowledgment

This research was supported by the Science and Technology Commission of Nanjing, Jiangsu Province, China (Project No. 2012-01032) and the Open Fund of Jiangsu Center for Research & Development of Medicinal Plants (No. 201202).

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Authors and Affiliations

  1. Jiangsu Center for Research & Development of Medicinal Plants, Jiangsu Institute of Botany, Chinese Academy of Sciences, Nanjing Botanical Garden, Mem. Sun Yat-Sen, 210014, Nanjing, P. R. China

    Min Yin, Chaocheng Xiao, Yu Chen, Wang Ming, Fuqin Guan, Yunfa Dong & Xu Feng

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  1. Min Yin
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  2. Chaocheng Xiao
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  3. Yu Chen
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  4. Wang Ming
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  5. Fuqin Guan
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  6. Yunfa Dong
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  7. Xu Feng
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Correspondence to Xu Feng.

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Published in Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2015, pp. 430–433.

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Yin, M., Xiao, C., Chen, Y. et al. Two New Sesquiterpenoid Glycosides from Rhizomes of Atractylodes lancea . Chem Nat Compd 51, 495–499 (2015). https://doi.org/10.1007/s10600-015-1323-7

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  • DOI: https://doi.org/10.1007/s10600-015-1323-7

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