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Synthesis of conjugates of 2′,3′-dideoxynucleoside-5′-monophosphates with α-amino acids

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Abstract

Previously undescribed conjugates of 2′,3′-dideoxyuridine-5′-monophosphate-(L)-methoxytryptophylphosphoramidate (5) and 2′,3′-dideoxycytidine-5′-monophosphate-(L)-methoxytryptophylphosphoramidate (7) were isolated by a chemical enzymatic method in order to study their pharmacological properties and to prepare new medicinal preparations based on them.

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Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 173–175, March–April, 2006.

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Zhernosek, E.V., Kvach, S.V., Eroshevskaya, L.A. et al. Synthesis of conjugates of 2′,3′-dideoxynucleoside-5′-monophosphates with α-amino acids. Chem Nat Compd 42, 208–211 (2006). https://doi.org/10.1007/s10600-006-0080-z

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  • DOI: https://doi.org/10.1007/s10600-006-0080-z

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