Abstract
A series of acetylene derivatives of thiazole using the Sonogashira cross-coupling method was synthesized and evaluated in vivo for their anti-inflammatory activity. Four compounds exhibited good anti-inflammatory activity and two inhibited soybean lipoxygenase.
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Published in Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 769–774, May, 2006.
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Geronikaki, A., Vasilevsky, S., Hadjipavlou-Litina, D. et al. Synthesis and anti-inflammatory activity of ethynylthiazoles. Chem Heterocycl Compd 42, 675–680 (2006). https://doi.org/10.1007/s10593-006-0145-8
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DOI: https://doi.org/10.1007/s10593-006-0145-8