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Cellulose-chitosan beads crosslinked by dialdehyde cellulose

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Abstract

Crosslinked cellulose-chitosan beads were obtained via dissolution-regeneration of cellulose and chitosan by a LiOH/urea aqueous solution, followed by the crosslinking of chitosan via dialdehyde cellulose (DAC). This crosslinking reaction involved the Schiff base formation between the aldehyde groups of DAC and the amino groups of chitosan and subsequent reduction. DAC was prepared through periodate oxidation of cellulose and solubilization in hot water at 100 °C for 1 h. Four grades of DAC-crosslinked cellulose-chitosan were prepared by controlling the amount of cellulose and chitosan. The DAC-crosslinked cellulose-chitosan showed higher stability in the pH range of 2–9 over a long-term 21-day test. Additionally, the DAC-crosslinked chitosan showed a higher bovine serum albumin adsorption capacity as a result of the increased amino group content due to the crosslinking between DAC and chitosan, which occurred at multiple points in spite of a lower degree in crosslinking.

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Acknowledgments

This research was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (NRF-2015R1D1A1A01058918).

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Authors and Affiliations

  1. Department of Plant and Environmental New Resources, College of Life Sciences, Kyung Hee University, 1732 Deogyeong-daero, Giheung-gu, Yongin-si, Gyeonggi-do, 446-701, Republic of Korea

    Ung-Jin Kim, Satoshi Kimura & Masahisa Wada

  2. Graduate School of Biotechnology, Kyung Hee University, 1732 Deogyeong-daero, Giheung-gu, Yongin-si, Gyeonggi-do, 446-701, Republic of Korea

    Ung-Jin Kim & Hyeon Joo Kim

  3. Graduate School of International Agricultural Technology and Institute of Green-bio Science and Technology, Seoul National University, Pyeongchang, Gangwon-do, 26354, Republic of Korea

    Joon Weon Choi

  4. Department of Biomaterials Science, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo, 113-8657, Japan

    Satoshi Kimura

  5. Division of Forest and Biomaterials Science, Graduate School of Agriculture, Kyoto University, Sakyo-ku, Kyoto, 606-8502, Japan

    Masahisa Wada

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  1. Ung-Jin Kim
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  2. Hyeon Joo Kim
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  3. Joon Weon Choi
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  4. Satoshi Kimura
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  5. Masahisa Wada
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Correspondence to Ung-Jin Kim or Masahisa Wada.

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Kim, UJ., Kim, H.J., Choi, J.W. et al. Cellulose-chitosan beads crosslinked by dialdehyde cellulose. Cellulose 24, 5517–5528 (2017). https://doi.org/10.1007/s10570-017-1528-y

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  • DOI: https://doi.org/10.1007/s10570-017-1528-y

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