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Distance from residence to power line and risk of childhood leukemia: a population-based case–control study in Denmark

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Abstract

Purpose

Epidemiological studies have found an association between exposure to extremely low-frequency magnetic fields (ELF-MF) and childhood leukemia. In 2005, a large British study showed an association between proximity of residence to high-voltage power lines and the risk of childhood leukemia. The association extended beyond distances at which the ‘power line’-induced magnetic fields exceed background levels, suggesting that the association was not explained by the magnetic field, but might be due to chance, bias, or other risk factors associated with proximity to power lines. Our aim was to conduct a comparable study in an independent setting (Denmark).

Methods

We included 1,698 cases aged <15, diagnosed with leukemia during 1968–2006, from the Danish Cancer Registry and 3,396 controls randomly selected from the Danish childhood population and individually matched by gender and year of birth. We used geographical information systems to determine the distance between residence at birth and the nearest 132–400 kV overhead power line.

Results

Odds ratios (ORs) were 0.76 [95 % confidence interval (CI) 0.40–1.45] for children who lived 0–199 m from the nearest power line and 0.92 (95 % CI 0.67–1.25) for those who lived 200–599 m away when compared with children who lived ≥600 m away. When restricting the analysis to 220 and 400 kV overhead power lines, the OR for children who lived 200–599 m from a power line was 1.76 (95 % CI 0.82–3.77) compared to children who lived ≥600 m away. However, chance is a likely explanation for this finding as the result was not significant, numbers were small, and there were no indications of an higher risk closer to the lines since no cases were observed within 200 m of these.

Conclusions

We found no higher risk of leukemia for children living 0–199 m or for children living 200–599 m of a 132–400 kV overhead power line. A slightly elevated OR for children living between 200 and 599 m of a 220–400 kV overhead power line is likely to be a chance finding.

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References

  1. Wertheimer N, Leeper E (1979) Electrical wiring configurations and childhood cancer. Am J Epidemiol 109:273–284

    CAS  PubMed  Google Scholar 

  2. Ahlbom A, Day N, Feychting M, Roman E, Skinner J, Dockerty J, Linet M, McBride M, Michaelis J, Olsen JH, Tynes T, Verkasalo PK (2000) A pooled analysis of magnetic fields and childhood leukaemia. Br J Cancer 83:692–698

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  3. Greenland S, Sheppard AR, Kaune WT, Poole C, Kelsh MA (2000) A pooled analysis of magnetic fields, wire codes, and childhood leukemia. Childhood Leukemia-EMF Study Group. Epidemiology 11:624–634

    Article  CAS  PubMed  Google Scholar 

  4. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans (2002) Non-ionizing radiation, Part 1: Static and extremely low-frequency (ELF) electric and magnetic fields. In: Monographs on the Evaluation of Carcinogenic Risks to Humans volume 80. IARC Press, Lyon

  5. Kheifets L, Ahlbom A, Crespi CM, Draper G, Hagihara J, Lowenthal RM, Mezei G, Oksuyan S, Schüz J, Swanson J, Tittarelli A, Vincetu M, Wunsch Filho V (2010) Pooled analysis of recent studies on magnetic fields and childhood leukaemia. Br J Cancer 103:1128–1135

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  6. WHO (2007) Extremely low frequency fields. World Health Organization: Geneva (Environmental Health Criteria 238)

  7. Schüz J, Ahlbom A (2008) Exposure to electromagnetic fields and the risk of childhood leukaemia: a review. Radiat Prot Dosim 132:202–211

    Article  Google Scholar 

  8. Draper G, Vincent T, Kroll ME, Swanson J (2005) Childhood cancer in relation to distance from high voltage power lines in England and Wales: a case–control study. BMJ 330:1290–1292

    Article  PubMed  Google Scholar 

  9. Kroll ME, Swanson J, Vincent TJ, Draper GJ (2010) Childhood cancer and magnetic fields from high-voltage power lines in England and Wales: a case–control study. Br J Cancer 103:1122–1127

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  10. Maslanyj M, Simpson J, Roman E, Schüz J (2009) Power frequency magnetic fields and risk of childhood leukaemia: misclassification of exposure from the use of the ‘distance from power line’ exposure surrogate. Bioelectromagnetics 30:183–188

    Article  PubMed  Google Scholar 

  11. Kheifets L, Feychting M, Schüz J (2005) Childhood cancer and power lines: results depend on chosen control group. BMJ 331:635–637

    Article  PubMed  Google Scholar 

  12. Feychting M, Ahlbom A (1993) Magnetic fields and cancer in children residing near Swedish high-voltage power lines. Am J Epidemiol 138:467–481

    CAS  PubMed  Google Scholar 

  13. Olsen JH, Nielsen A, Schulgen G (1993) Residence near high voltage facilities and risk of cancer in children. BMJ 307:891–895

    Article  CAS  PubMed  Google Scholar 

  14. Tynes T, Haldorsen T (1997) Electromagnetic fields and cancer in children residing near Norwegian high-voltage power lines. Am J Epidemiol 145:219–226

    Article  CAS  PubMed  Google Scholar 

  15. McBride ML, Gallagher RP, Theriault G, Armstrong BG, Tamaro S, Spinelli JJ, Deadman JE, Fincham S, Robson D, Choi W (1999) Power-frequency electric and magnetic fields and risk of childhood leukemia in Canada. Am J Epidemiol 149:831–842

    Article  CAS  PubMed  Google Scholar 

  16. Kleinerman RA, Kaune WT, Hatch EE, Wacholder S, Linet MS, Robison LL, Niwa S, Tarone RE (2000) Are children living near high-voltage power lines at increased risk of acute lymphoblastic leukemia? Am J Epidemiol 151:512–515

    Article  CAS  PubMed  Google Scholar 

  17. UK Childhood Cancer Study Investigators (2000) Childhood cancer and residential proximity to power lines. UK Childhood Cancer Study Investigators. Br J Cancer 83:1573–1580

    Article  PubMed Central  Google Scholar 

  18. Sermage-Faure C, Demoury C, Rudant J, Goujon-Bellec S, Guyot-Goubin A, Deschamps F, Hemon D, Clavel J (2013) Childhood leukaemia close to high-voltage power lines—the Geocap study, 2002–2007. Br J Cancer 108:1899–1906

    Article  CAS  PubMed  Google Scholar 

  19. Wunsch-Filho V, Pelissari DM, Barbieri FE, Sant’Anna L, de Oliveira CT, de Mata JF, Tone LG, Lee ML, de Andrea ML, Bruniera P, Epelman S, Filho VO, Kheifets L (2011) Exposure to magnetic fields and childhood acute lymphocytic leukemia in Sao Paulo, Brazil. Cancer Epidemiol 35:534–539

    Article  PubMed  Google Scholar 

  20. Gjerstorff ML (2011) The Danish Cancer Registry. Scand J Public Health 39:42–45

    Article  PubMed  Google Scholar 

  21. Raaschou-Nielsen O, Obel J, Dalton S, Tjønneland A, Hansen J (2004) Socioeconomic status and risk of childhood leukaemia in Denmark. Scand J Public Health 32:279–286

    Article  PubMed  Google Scholar 

  22. Feychting M, Kaune WT, Savitz DA, Ahlbom A (1996) Estimating exposure in studies of residential magnetic fields and cancer: importance of short-term variability, time interval between diagnosis and measurement, and distance to power line. Epidemiology 7:220–224

    Article  CAS  PubMed  Google Scholar 

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Acknowledgments

This work was supported by a grant by the foundation Children with Cancer UK (formerly Children with Leukemia), by Danish Energy for provision and estimation of exposure data; and by the Danish Cancer Society.

Conflict of interest

The authors declare that they have no conflict of interest.

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Correspondence to Camilla Pedersen.

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Pedersen, C., Raaschou-Nielsen, O., Rod, N.H. et al. Distance from residence to power line and risk of childhood leukemia: a population-based case–control study in Denmark. Cancer Causes Control 25, 171–177 (2014). https://doi.org/10.1007/s10552-013-0319-5

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  • DOI: https://doi.org/10.1007/s10552-013-0319-5

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