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Comparative Analysis of MMP-8 and MMP-9 Concentrations in Crevicular and Peri-Implants Sulcular Fluids

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The concentrations of MMP-8 and MMP-9 were measured in the crevicular and the peri-implant sulcular fluids at the different stages of the prosthetic treatment. The concentration MMP-8 and MMP-9 in the peri-implant sulcular fluids were significantly higher (p<0.05) then in the gingival crevicular fluid. The determined parameters are the references values for dynamic observation over the functional state of the dental “implant—bone—soft” tissue system. The detected the correlations attest to synergy between secretion of MMP-8 and MMP-9 in the peri-implant sulcular fluid and allow analysis of the dependence of the secretion of these metalloproteinases on clinical and physiological peculiarities of the gingiva, which will help to better customize implant-supported prosthetic treatment of the patients.

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Authors and Affiliations

  1. Department of Orthopedic Dentistry, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia

    T. V. Kaliyatz & E. A. Solovykh

  2. A. I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of the Russian Federation, Moscow, Russia

    E. S Gershtein & N. E. Kushlinskii

Authors
  1. T. V. Kaliyatz
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  2. E. A. Solovykh
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  3. E. S Gershtein
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  4. N. E. Kushlinskii
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Corresponding author

Correspondence to E. A. Solovykh.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 170, No. 7, pp. 26-32, July, 2020

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Kaliyatz, T.V., Solovykh, E.A., Gershtein, E.S. et al. Comparative Analysis of MMP-8 and MMP-9 Concentrations in Crevicular and Peri-Implants Sulcular Fluids. Bull Exp Biol Med 170, 19–23 (2020). https://doi.org/10.1007/s10517-020-04996-2

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  • DOI: https://doi.org/10.1007/s10517-020-04996-2

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