The effects of amygdaline from apricot kernel added to fodder on the growth of transplanted LYO-1 and Ehrlich carcinoma were studied in mice. Apricot kernels inhibited the growth of both tumors. Apricot kernels, raw and after thermal processing, given 2 days before transplantation produced a pronounced antitumor effect. Heat-processed apricot kernels given in 3 days after transplantation modified the tumor growth and prolonged animal lifespan. Thermal treatment did not considerably reduce the antitumor effect of apricot kernels. It was hypothesized that the antitumor effect of amygdaline on Ehrlich carcinoma and LYO-1 lymphosarcoma was associated with the presence of bacterial genome in the tumor.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 160, No. 11, pp. 669-671, November, 2015
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Yamshanov, V.A., Kovan’ko, E.G. & Pustovalov, Y.I. Effects of Amygdaline from Apricot Kernel on Transplanted Tumors in Mice. Bull Exp Biol Med 160, 712–714 (2016). https://doi.org/10.1007/s10517-016-3257-x
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DOI: https://doi.org/10.1007/s10517-016-3257-x