Administration of standardized drinking water containing 10 mg/liter silicon for 2 months adlibitum induced structural reorganization of the cortical and medullary layers of the thymiclobules in laboratory rats accompanied by functional activation of monocyte/macrophage cells and antigen-presenting cells was changed in morphological structures of the thymus. A possible mechanism of development of autoimmune processes under the effect of silicon is discussed.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 158, No. 12, pp. 786-790, December, 2014
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Gordova, V.S., Dyachkova, I.M., Sergeeva, V.E. et al. Morphofunctional Adaptation of Rat Thymus Structures to Silicon Consumption with Drinking Water. Bull Exp Biol Med 158, 816–819 (2015). https://doi.org/10.1007/s10517-015-2869-x
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DOI: https://doi.org/10.1007/s10517-015-2869-x