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Activities of Clotting, Fibrinolytic, and Anticoagulant Components of Plasma Hemostasis in Patients with Degenerative Diseases of Large Joints

  • Experimental Methods for Clinical Practice
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Bulletin of Experimental Biology and Medicine Aims and scope

Analysis of plasma hemostasis parameters was carried out in 110 patients with degenerative diseases of hip or knee joints hospitalized for initial endoprosthetics. Molecular markers of clotting and fibrinolysis and physiological anticoagulants were studied. Activities of all components of plasma hemostasis were normal in 29.4% patients. In 54.1% patients, high clotting activity was compensated for by adequate fibrinolysis activity. High thrombin formation was compensated for by high consumption of physiological anticoagulants in 10.1% patients. In 6.4% patients, high clotting activity was not paralleled by high fibrinolytic activity.

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Authors and Affiliations

  1. V. D. Chaklin Ural Institute of Traumatology and Orthopedics, Ministry of Health Care and Social Development of the Russian Federation, Ekaterinburg, Russia

    I. P. Antropova

  2. Institute of Immunology and Physiology, Ural Division of the Russian Academy of Sciences, Ekaterinburg, Russia

    B. G. Yushkov

Authors
  1. I. P. Antropova
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  2. B. G. Yushkov
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Correspondence to I. P. Antropova.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 153, No. 4, pp. 495-498, April, 2012

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Antropova, I.P., Yushkov, B.G. Activities of Clotting, Fibrinolytic, and Anticoagulant Components of Plasma Hemostasis in Patients with Degenerative Diseases of Large Joints. Bull Exp Biol Med 153, 505–507 (2012). https://doi.org/10.1007/s10517-012-1752-2

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  • DOI: https://doi.org/10.1007/s10517-012-1752-2

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