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In Vitro Effect of Knotolan, a New Lignan from Abies sibirica, on the Growth of Hormone-Dependent Breast Cancer Cells

  • Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

An Erratum to this article was published on 01 February 2011

Here we present antiestrogenic effects of Knotolan®, a new dietary lignan from Abies sibirica raw material. Knotolan abolished growth-stimulating effects of 17β-estragiol on hormonedependent MCF-7 cells.

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Authors and Affiliations

  1. N. N. Blokhin Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia

    O. S. Zhukova, L. V. Fetisova, A. V. Trishin, N. Yu. Anisimova, A. E. Shcherbakov & M. V. Kiselevskii

  2. N. D. Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia

    D. V. Yashunskii, D. E. Tsvetkov, V. M. Men’shov & N. E. Nifant’ev

Authors
  1. O. S. Zhukova
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  2. L. V. Fetisova
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  3. A. V. Trishin
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  4. N. Yu. Anisimova
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  5. A. E. Shcherbakov
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  6. D. V. Yashunskii
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  7. D. E. Tsvetkov
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  8. V. M. Men’shov
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  9. M. V. Kiselevskii
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  10. N. E. Nifant’ev
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Corresponding author

Correspondence to M. V. Kiselevskii.

Additional information

Translated from Kletochnye Tehnologii v Biologii i Medicine, No. 2, pp. 78–81, April, 2010

An erratum to this article can be found at http://dx.doi.org/10.1007/s10517-011-1188-0

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Zhukova, O.S., Fetisova, L.V., Trishin, A.V. et al. In Vitro Effect of Knotolan, a New Lignan from Abies sibirica, on the Growth of Hormone-Dependent Breast Cancer Cells. Bull Exp Biol Med 149, 511–514 (2010). https://doi.org/10.1007/s10517-010-0981-5

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  • DOI: https://doi.org/10.1007/s10517-010-0981-5

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