Dihydroquercetin (flavonoid of plant origin) immobilized with an amino acid in lecithin nanoparticles promotes reduction of inflammatory reactions in the wound after thermal burn. The use of a liposomal complex in burn injury stabilizes endogenous antioxidant system and limits the secondary necrotic zone in the wounds. The treatment was associated with intensification of skin regeneration processes and reparation of hairy follicles and sebaceous glands.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
A. A. Naumov, Yu. V. Shatalin, T. K. Sukhomlin, and M. M. Potselueva, Kletochn. Tekhnol. Biol. Med., No. 2, 96–102 (2009).
M. M. Potselueva, A. V. Pustovidko, V. S. Alabin, and Yu. V. Evtodienko, Tsitologiya, 41, No. 2, 162–166 (1999).
M. M. Potselueva, A. V. Pustovidko, E. V. Kovaleva, and Yu. V. Shatalin, Ibid., 47, No. 1, 57–63 (2005).
A. N. Saprin and E. V. Kalinina, Uspekhi Biol. Khim., 39, 289–326 (1999).
V. V. Semchenko, S. A. Barashkova, V. I. Nozdrin, and V. N. Artemyev, Histological Methods [in Russian], Omsk (2006), P. 78–85.
A. A. Ton’shin, N. V. Lobysheva, L. S. Yaguzhinskii, et al., 72, No. 5, 622–630 (2007).
C. Bronner and Y. Landry, Agents Actions, 16, Nos. 3–4, 147–151 (1985).
J. A. Knight, Ann. Clin. Lab. Sci., 28, No. 6, 331–346 (1998).
N. Sugihara, T. Arakawa, M. Ohnishi, and K. Furuno, Free Radic. Biol. Med., 27, No. 11–12, 1313–1323 (1999).
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 149, No. 1, pp. 69–73, January, 2010
Rights and permissions
About this article
Cite this article
Naumov, A.A., Shatalin, Y.V. & Potselueva, M.M. Effects of a Nanocomplex Containing Antioxidant, Lipid, and Amino Acid on Thermal Burn Wound Surface. Bull Exp Biol Med 149, 62–66 (2010). https://doi.org/10.1007/s10517-010-0876-5
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10517-010-0876-5