Abstract
Medical image segmentation is a crucial task in many clinical applications, such as tumor detection and surgical planning. However, the annotation process for medical images is often both time-consuming and expensive, which requires professional knowledge and experience. This study aims to develop a medical image segmentation method based on semi-supervised learning, which can improve the performance of segmentation by effectively using labeled data and unlabeled data. We proposed a novel multi-task semi-supervised method based on multi-branch cross pseudo supervision, called MS2MPS, which can efficiently utilize unlabeled data for semi-supervised medical image segmentation. The proposed method consists of two multi-task backbone networks with multiple output branches, which were used to simultaneously generate segmentation probability maps (SPM) and signed distance maps (SDM) to get more constraints and information. Moreover, a multi-branch cross pseudo supervised (MPS) approach was proposed to promote the high similarity between predictions of the same input image by multiple perturbation networks. Experiments on the public medical image segmentation dataset Automated Cardiac Diagnosis Challenge (ACDC) and Left Atrium (LA) dataset demonstrate that our approach is superior to existing some semi-supervised segmentation methods in terms of Dice similarity coefficient (DSC), 95% Hausdorff distance (HD95), and Jaccard Similarity Coefficient (JSC). When trained with 10% labeled data, compared to the best results in all compared methods, our approach improved the DSC by 2.63% and 1.54% on the ACDC and LA datasets, increased the JSC by 23.15% and 0.79%, and simultaneously reduced the HD95 by 12.57% and 7.77% on the respective datasets. Our proposed semi-supervised medical image segmentation approach is an effective and practical solution for medical image analysis, particularly in scenarios where labeled data is limited or expensive.
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Acknowledgements
This work was supported by the National Natural Science Foundation of China under grant 12071215 and the Postgraduate Research & Practice Innovation Program of Jiangsu Province [Project number KYCX23 0364].
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Yueyue xiao: Conceptualization, Methodology, Software, Validation, Writing-original draft. Yuan Zou:Data preprocessing, Software, Validation, and analysis. Chunxiao chen: Conceptualization, Writing - review & supervision. Xue Fu Liang Wang, and Jie Yu: Formal analysis and investigation. Huiyu Zhou: review. All authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.
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Xiao, Y., Chen, C., Fu, X. et al. A novel multi-task semi-supervised medical image segmentation method based on multi-branch cross pseudo supervision. Appl Intell 53, 30343–30358 (2023). https://doi.org/10.1007/s10489-023-05158-3
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DOI: https://doi.org/10.1007/s10489-023-05158-3