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Diagnosis of anaemia: old things rearranged

Anämiediagnose: alte Zöpfe neu geflochten

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Summary

Anaemia is one of the most leading causes of morbidity and mortality, as declared by the World Health Organisation. This syndrome is characterised by low haemoglobin levels and nonspecific clinical symptoms such as weakness, fatigue and dyspnoea. The symptoms are unspecific as the underlying causes are heterogeneous. Thus, good knowledge of the useful bisickomarkers and their correct assignment is needed to allow rapid and targeted diagnosis.

Zusammenfassung

Laut Weltgesundheitsorganisation ist die Anämie eine der häufigsten Ursachen für Morbidität und Mortalität. Dieses Syndrom ist durch einen erniedrigten Hämoglobinspiegel charakterisiert, sowie durch unspezifische klinische Symptome wie Schwächegefühl, Müdigkeit und Atemnot. So unspezifisch wie die Symptome sind, so unterschiedlich sind die Ursachen für eine Anämie. Daher sind gute Kenntnisse über den richtigen und sinnvollen Einsatz von Biomarkern notwendig, um eine schnelle und zielgerichtete Diagnose stellen zu können.

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Notes

  1. Serum transferrin (TF) (g/l) = 0.007 ´ Total iron-binding capacity (TIBC) (mg/l)

    TIBC (mg/dl) = TF (mg/dl) ´ 1.41

    TIBC (mmol/l) = TF (g/l) ´ 25.2

    Transferrin saturation (TSAT) (%) = serum iron (mg/dl)/TF (mg/dl) ´ 70.9

    TSAT (%) = serum iron (mmol/l)/TF (mg/dl) ´ 398

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  1. Department for Laboratory Medicine, Central Hospital Steyr, Sierningerstrasse 170, 4400, Steyr, Austria

    Gabriele Halwachs-Baumann MSc, MBA

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Halwachs-Baumann, G. Diagnosis of anaemia: old things rearranged. Wien Med Wochenschr 162, 478–488 (2012). https://doi.org/10.1007/s10354-012-0149-1

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