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Application value of simultaneous multislice readout-segmented echo-planar imaging for diffusion-weighted MRI in differentiation of rectal cancer grade

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Abstract

Objective

To analyze the association of apparent diffusion coefficient (ADC) values measured by readout-segmented echo-planar imaging (rs-EPI) using different simultaneous multislice (SMS) acceleration factors and the differentiation of rectal cancer grade.

Materials and methods

Patients with non-mucinous rectal adenocarcinoma diagnosed by biopsy (endoscope-guided biopsy or surgical resection) were retrospectively collected, and each patient underwent an MRI examination. ADC values of rs-EPI, 2 × SMS rs-EPI, and 3 × SMS rs-EPI were recorded as ADC1, ADC2, and ADC3, respectively.

Results

The scanning time of 2 × SMS rs-EPI was 60 s, 56.2% shorter than 137 s of rs-EPI sequence, while that of 3 × SMS rs-EPI was 51 s, 72.8% less than that of rs-EPI time. The ADC value of the three groups dropped with the decrease in cancer grade (p < 0.05). The AUC values of ADC1, ADC2, and ADC3 in predicting highly differentiated rectal cancer were 0.74, 0.729, and 0.687, respectively. The difference in AUC values between ADC1 and ADC2 was not statistically significant (p = 0.889).

Discussion

SMS technology with an acceleration factor of 2 could be applied clinically to evaluate the pathological differentiation of rectal cancer grade.

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Author notes

  1. Mi Zhou and Hongyun Huang are co-first authors.

Authors and Affiliations

  1. Department of Radiology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, No. 32, West Second Section of First Ring Road, Qingyang District, Chengdu, 610072, People’s Republic of China

    Mi Zhou, Hongyun Huang, Hang Li, Guihua Yan & Yuting Wang

  2. Department of Pathology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, West Second Section of First Ring Road, Qingyang District, Chengdu, 610072, People’s Republic of China

    Baijie Tang

  3. Department of MR Scientific Marketing, Siemens Healthineers, Shanghai, 200135, People’s Republic of China

    Meining Chen

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Correspondence to Yuting Wang.

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Zhou, M., Huang, H., Li, H. et al. Application value of simultaneous multislice readout-segmented echo-planar imaging for diffusion-weighted MRI in differentiation of rectal cancer grade. Magn Reson Mater Phy 36, 621–629 (2023). https://doi.org/10.1007/s10334-022-01054-y

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