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Impact of Breast Density on Computer-Aided Detection in Full-Field Digital Mammography

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The goal of this study was to evaluate the performance of a computer-aided detection (CAD) system in full-field digital mammography (Senographe 2000D, General Electric, Buc, France) in finding out carcinomas depending on the parenchymal density. A total of 226 mediolateral oblique (MLO) and 186 craniocaudal (CC) mammographic views of histologically proven cancers were retrospectively evaluated with a digital CAD system (ImageChecker V2.3 R2 Technology, Los Altos, CA, USA). Malignant tumors were detected correctly by CAD in MLO view in 84.85% in breasts with parenchymal tissue density of the American College of Radiology (ACR) type 1, in 70.33% of the ACR type 2, in 68.12% of the ACR type 3, and in 69.70% of the ACR type 4. For the CC view, similar results were found according to the ACR types. Using the chi-square and McNemar tests, there was no statistical significance. However, a trend of better detection could be seen with decreasing ACR type. In conclusion, there seems to be a tendency for breast tissue density to affect the detection rate of breast cancer when using the CAD system.

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Authors and Affiliations

  1. Department of Radiology, Georg August University, Robert-Koch-Str. 40, Göttingen Niedersachsen, 37 075, Germany

    Silvia Obenauer, Christian Sohns & Eckhardt Grabbe

  2. Department of Medical Statistics, Georg August University, Robert-Koch-Str. 40, Göttingen Niedersachsen, 37 075, Germany

    Carola Werner

Authors
  1. Silvia Obenauer
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  2. Christian Sohns
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  3. Carola Werner
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  4. Eckhardt Grabbe
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Correspondence to Silvia Obenauer.

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Obenauer, S., Sohns, C., Werner, C. et al. Impact of Breast Density on Computer-Aided Detection in Full-Field Digital Mammography. J Digit Imaging 19, 258–263 (2006). https://doi.org/10.1007/s10278-006-0592-x

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  • DOI: https://doi.org/10.1007/s10278-006-0592-x

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