Abstract
Automobile crashes and blunt trauma often lead to life-threatening thoracic injuries, especially to the lung tissues. These injuries can be simulated using finite element-based human body models that need dynamic material properties of lung tissue. The strain-rate-dependent material parameters of human parenchymal tissues were determined in this study using uniaxial quasi-static (1 mm/s) and dynamic (1.6, 3, and 5 m/s) compression tests. A bilinear material model was used to capture the nonlinear behavior of the lung tissue, which was implemented using a user-defined material in LS-DYNA. Inverse mapping using genetic algorithm-based optimization of all experimental data with the corresponding FE models yielded a set of strain-rate-dependent material parameters. The bilinear material parameters are obtained for the strain rates of 0.1, 100, 300, and 500 s−1. The estimated elastic modulus increased from 43 to 153 kPa, while the toe strain reduced from 0.39 to 0.29 when the strain rate was increased from 0.1 to 500 s−1. The optimized bilinear material properties of parenchymal tissue exhibit a piecewise linear relationship with the strain rate.
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The data that support the findings within this study are available from the corresponding author upon a reasonable request.
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The authors acknowledge the financial support received from Joint Advanced Technology Centre, DRDO (DFTM/03/3203/M/01/JATC).
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YSP and AN performed the experimental studies, developed optimization methodology and wrote the manuscript. RM and SL gave the inputs on the human tissues from AIIMS, India. AC, SM, and NVD contributed to conceptualization, supervision, editing the manuscript and arranging the support from the funding agency.
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Pydi, Y.S., Nath, A., Chawla, A. et al. Strain-rate-dependent material properties of human lung parenchymal tissue using inverse finite element approach. Biomech Model Mechanobiol 22, 2083–2096 (2023). https://doi.org/10.1007/s10237-023-01751-0
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DOI: https://doi.org/10.1007/s10237-023-01751-0