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A case of cutaneous polyarteritis nodosa with elevated serum interleukin-6 levels complicated by leg arterial stenosis and destructive arthropathy of the left ankle

  • Case Report
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Modern Rheumatology

Abstract

We report a case of a 60-year-old female with cutaneous polyarteritis nodosa (CPN) of the left ankle, accompanied by elevated serum interleukin (IL)-6 levels. Computed tomographic angiography revealed severe narrowing of medium-sized arteries in her left leg. Destructive arthropathy in the left ankle was identified by X-ray and magnetic resonance imaging. This is the first Japanese case of severe CPN complicated by destructive arthropathy. Quantification of serum IL-6 might be useful in diagnosis and evaluation of CPN.

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Authors and Affiliations

  1. Unit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan

    Yoshiro Horai, Ayuko Tokuyama, Remi Sumiyoshi, Yoshikazu Nakashima, Takahisa Suzuki, Akitomo Okada, Shin-ya Kawashiri, Kunihiro Ichinose, Mami Tamai, Satoshi Yamasaki, Hideki Nakamura & Atsushi Kawakami

  2. Department of General Internal Medicine and Rheumatology, National Hospital Organization Nagasaki Medical Center, Omura, Nagasaki, 856-8562, Japan

    Yasumori Izumi & Taiichiro Miyashita

  3. Department of Pathology, Nagasaki University Hospital, Nagasaki, 852-8501, Japan

    Tomayoshi Hayashi

  4. Unit of Translational Medicine, Department of Rehabilitation Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, 852-8523, Japan

    Tomoki Origuchi

Authors
  1. Yoshiro Horai
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  2. Ayuko Tokuyama
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  3. Remi Sumiyoshi
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  4. Yoshikazu Nakashima
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  5. Takahisa Suzuki
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  6. Akitomo Okada
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  7. Shin-ya Kawashiri
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  8. Kunihiro Ichinose
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  9. Yasumori Izumi
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  10. Taiichiro Miyashita
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  11. Mami Tamai
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  12. Satoshi Yamasaki
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  13. Hideki Nakamura
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  14. Tomayoshi Hayashi
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  15. Tomoki Origuchi
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  16. Atsushi Kawakami
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Corresponding author

Correspondence to Yoshiro Horai.

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Horai, Y., Tokuyama, A., Sumiyoshi, R. et al. A case of cutaneous polyarteritis nodosa with elevated serum interleukin-6 levels complicated by leg arterial stenosis and destructive arthropathy of the left ankle. Mod Rheumatol (2012). https://doi.org/10.1007/s10165-012-0753-3

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  • DOI: https://doi.org/10.1007/s10165-012-0753-3

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