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l-Arginine prevents stroke-like episodes but not brain atrophy: a 20-year follow-up of a MELAS patient

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References

  1. El-hattab AW, Adesina AM, Jones J, Scaglia F (2015) MELAS syndrome: clinical manifestations , pathogenesis , and treatment options. Mol Genet Metab 116(1–2):4–12. https://doi.org/10.1016/j.ymgme.2015.06.004

    Article  CAS  PubMed  Google Scholar 

  2. Iizuka T, Sakai F, Suzuki N, Hata T, Tsukahara S, Fukuda M, Takiyama Y (2002) Neuronal hyperexcitability in stroke-like episodes of MELAS syndrome. Neurology 59(6):816–824. https://doi.org/10.1212/WNL.59.6.816

    Article  CAS  PubMed  Google Scholar 

  3. El-Hattab AW, Emrick LT, Chanprasert S, Craigen WJ, Scaglia F (2014) Mitochondria: role of citrulline and arginine supplementation in MELAS syndrome. Int J Biochem Cell Biol 48(1):85–91. https://doi.org/10.1016/j.biocel.2013.12.009

    Article  CAS  PubMed  Google Scholar 

  4. Koga Y, Akita Y, Nishioka J, Yatsuga S, Povalko N, Tanabe Y, Fujimoto S, Matsuishi T (2005) L-arginine improves the symptoms of stroke-like episodes in MELAS. Neurology 64:710–712

    Article  CAS  Google Scholar 

  5. DiMauro S, Hirano M, Schon E A (2000) Mitochondrial encephalomyopathies: therapeutic approaches. [Review] [75 refs]. Neurol Sci 21(5:Suppl) Suppl-8

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Acknowledgements

We thank the patient and her family, as well as the medical staff of the Peking Union Medical College Hospital.

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Authors and Affiliations

  1. Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shuaifuyuan 1, Dongcheng district, Beijing, 100730, People’s Republic of China

    Yanping Wei, Liying Cui & Bin Pen

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  1. Yanping Wei
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  2. Liying Cui
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  3. Bin Pen
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Correspondence to Yanping Wei.

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Wei, Y., Cui, L. & Pen, B. l-Arginine prevents stroke-like episodes but not brain atrophy: a 20-year follow-up of a MELAS patient. Neurol Sci 40, 209–211 (2019). https://doi.org/10.1007/s10072-018-3573-1

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  • DOI: https://doi.org/10.1007/s10072-018-3573-1

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