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Idiopathic retroperitoneal fibrosis: an unusual cause of low back pain

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Abstract

Retroperitoneal fibrosis (RPF) is a rare inflammatory disease which is characterized by the development of a fibrous process that surrounds the major vessels and organs located within the retroperitoneum. About two thirds of all cases of RPF are idiopathic and are thought to be immunological in origin. Diagnosis of RPF should be considered in patients with unexplained abdominal and low back pain and retroperitoneal lesions. We present a case report of a 59-year-old white male with idiopathic RPF with history of low back pain and weight loss as only symptoms and treated by tamoxifen, corticosteroids, and insertion of JJ endoureteric catheters due to the obstruction of the upper urinary tract.

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References

  1. Ormond J (1948) Bilateral ureteral obstruction due to envelopment and compression by an inflammatory retroperitoneal process. J Urol 59:1072–1079

    PubMed  CAS  Google Scholar 

  2. McDougal WS, MacDonell RC Jr (1991) Treatment of idiopathic retroperitoneal fibrosis by immunosuppression. J Urol 145:112–114

    PubMed  CAS  Google Scholar 

  3. Hoffman WW, Trippel OH (1961) Retroperitoneal fibrosis: etiological considerations. J Urol 86:222–231

    PubMed  CAS  Google Scholar 

  4. Amis ES Jr (1991) Retroperitoneal fibrosis. AJR Am J Roentgenol 157:321–329

    PubMed  Google Scholar 

  5. Kinzbrunner B, Ritter S, Domingo J, Rosenthal CJ (1983) Remission of rapidly growing desmoid tumors after tamoxifen therapy. Cancer 52:2201–2204

    Article  PubMed  CAS  Google Scholar 

  6. Clark CP, Vanderpool D, Preskitt JT (1991) The response of retroperitoneal fibrosis to tamoxifen. Surgery 109:502–506

    PubMed  CAS  Google Scholar 

  7. Loffeld RJ, van Weel TF (1993) Tamoxifen for retroperitoneal fibrosis. Lancet 341:382

    Article  PubMed  CAS  Google Scholar 

  8. Ergun I, Keven K, Canbakan B, Ekmekci Y, Erbay B (2005) Tamoxifen in the treatment of idiopathic retroperitoneal fibrosis. Int Urol Nephrol 37:341–343

    Article  PubMed  CAS  Google Scholar 

  9. Degesys GE, Dunnick NR, Silverman PM, Cohan RH, Illescas FF, Castagno A (1986) Retroperitoneal fibrosis: use of CT in distinguishing among possible causes. AJR Am J Roentgenol 146:57–60

    PubMed  CAS  Google Scholar 

  10. Yuh WT, Barloon TJ, Sickels WJ, Kramolowsky EV, Williams RD (1989) Magnetic resonance imaging in the diagnosis and followup of idiopathic retroperitoneal fibrosis. J Urol 141:602–605

    PubMed  CAS  Google Scholar 

  11. Kubota Y, Nomura Y, Tamaki M, Maeda S, Deguchi T (2005) Four cases of idiopathic retroperitoneal fibrosis markedly responsive to steroid therapy. Hinyokika Kiyo 51:315–319

    PubMed  Google Scholar 

  12. Kardar AH, Kattan S, Lindstedt E, Hanash K (2002) Steroid therapy for idiopathic retroperitoneal fibrosis: dose and duration. J Urol 168:550–555

    Article  PubMed  CAS  Google Scholar 

  13. Hollingworth P, Denman AM, Gumpel JM (1980) Retroperitoneal fibrosis and polyarteritis nodosa successfully treated by intensive immunosuppression. J R Soc Med 73:61–64

    PubMed  CAS  Google Scholar 

  14. Maillart E, Laueriere L, Kassis S, Moulonguet-Doleris L, Prinseau J, Baglin A et al (2006) Is there an evidence-based management of idiopathic retroperitoneal fibrosis? Rev Med Interne 27:854–857

    Article  PubMed  CAS  Google Scholar 

  15. Horgan K, Cooke E, Hallett MB, Mansel RE (1986) Inhibition of protein kinase C mediated signal transduction by tamoxifen. Importance for antitumour activity. Biochem Pharmacol 35:4463–4465

    Article  PubMed  CAS  Google Scholar 

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Correspondence to Petr Nemec.

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Nemec, P., Rybnickova, S., Fabian, P. et al. Idiopathic retroperitoneal fibrosis: an unusual cause of low back pain. Clin Rheumatol 27, 381–384 (2008). https://doi.org/10.1007/s10067-007-0736-5

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  • DOI: https://doi.org/10.1007/s10067-007-0736-5

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