Abstract
The oxidation of ascorbic acid (AA) and dopamine (DA) is studied on non-modified and copper crystal-modified poly(3,4-ethylenedioxythiophene) (PEDOT)-coated electrodes. Both oxidation reactions are studied for different thickness of the polymer layers. For several microns thick PEDOT layers both PEDOT and Cu-modified PEDOT show the largest currents. A stable voltammetric response for AA oxidation is observed together with a linear dependence of the peak currents on concentration in the 0.3 to 6.0 mM range. For DA oxidation, however, a gradual loss of electroactivity is found with increasing number of voltammetric scans and concentration. This problem is overcome by using thinner (<1 µm) polymer layers. In the presence of both AA and DA, the Cu-modified PEDOT-coated electrodes provide better selectivity with respect to DA in comparison to non-modified PEDOT due to partial suppression of the AA oxidation currents. Thin PEDOT layers modified with electrodeposited Cu crystals show a stable and sensitive response for DA oxidation in the micromolar concentration range. A linear dependence of the voltammetric peak currents is found in a wide concentration range (from 6 to about 200 µM) of DA in the presence of a large excess (1 mM concentration) of AA. The sensitivity is 0.013 µA µM-1.
Similar content being viewed by others
References
Saraceno RA, Pack JG, Ewing AG (1986) J Electroanal Chem 197:265–278
Wang J, Li R (1989) Anal Chem 61:2809–2811
Mark HB Jr, Atta N, Ma YL, Petticrew KL, Zimmer H, Shi Y, Lunsford SK, Rubinson JF, Galal A (1995) Bioelectrochem Bioenerg 38:229–245
Wang J, Chen SP, Lin MS (1989) J Electroanal Chem 273:231–242
Atta MF, Galal A, Karagoezler AE, Russel GC, Zimmer H, Mark HB Jr (1991) Biosens Bioelectron 6:333–341
Atta NF, Marawi I, Petticrew KL, Zimmer H, Mark HB Jr, Galal A (1996) J Electroanal Chem 408:47–52
Erdogdu G, Mark HB Jr, Karagoezler AE (1996) Anal Lett 29:221–231
Erdogdu G, Karagoezler AE (1997) Talanta 44:2011–2018
Galal A (1998) J Solid State Electrochem 2:7–15
Wang HS, Li TH, Jia WL, Xu HY (2006) Biosens Bioelectron 22:664–669
Lupu S, Parenti F, Pigani L, Seeber R, Zanardi C (2003) Electroanalysis 15:715–725
Raoof JB, Ojani R, Rashid-Nadimi S (2005) Electrochim Acta 50:4694–4698
Fabre B, Taillebois L (2003) Chem Comm 24:2982–2983
Mathiyarasu J, Senthilkumar S, Phani KLN, Yegnaraman V (2005) J Appl Electrochem 35:513–519
Yin T, Wei W, Zeng J (2006) Anal Bioanal Chem 386:2087–2094
Zucolotto V, Ferreira M, Cordeiro MR, Constantino CJL, Moreira WC, Oliveira ON Jr (2006) Sens Act B 113:809–815
Forzani ES, Li X, Tao N (2007) Anal Chem 79:5217–5224
Ekinci E, Erdogdu G, Karagoezler AE (2001) J Appl Polym Sci 79:327–332
Selvaraju T, Ramaraj R (2003) J Appl Electrochem 33:759–762
Kumar SS, Mathiyarasu J, Phani KL, Jain Y, Yegnaraman V (2005) Electroanalysis 17:2281–2286
Senthil Kumar S, Mathiyarasu J, Phani KLN, Yegnaraman V (2006) J Solid State Electrochem 10:905–913
Vasantha VS, Chen SM (2006) J Electroanal Chem 592:77–87
Balamurugan A, Shen SM (2007) Anal Chim Acta 596:92–98
Lupu S, Lete C, Marin M, Totir N, Balaure PC (2009) Electrochim Acta 54:1932–1938
Gao ZQ, Ivaska A (1993) Anal Chem Acta 284:393–404
Gao ZQ, Chen BS, Zi MX (1994) Analyst 119:459–464
Hsueh CC, Brajter-Toth A (1994) Anal Chem 68:2458–2463
Zhang X, Ogorevc B, Tavcar G, Svegl IG (1996) Analyst 121:1817–1822
Pihel K, Walker QD, Wightman RM (1996) Anal Chem 68:2084–2089
Gao Z, Yap D, Zhang Y (1998) Anal Sci 14:1059–1063
Mo JW, Ogorevc B (2001) Anal Chem 73:1196–1202
Malinauskas A, Garjonyte R, Mazeikiene R, Jureviciute I (2004) Talanta 64:121–129
D’Eramo F, Sereno LE, Arevalo AH (2006) Electroanalysis 18:1523–1530
Senthil KS, Mathiyarasu J, Lakshminarasimha Phani K (2005) J Electroanal Chem 578:95–103
Li J, Lin X (2007) Sens Actuators B 124:486–493
Mathiyarasu J, Senthilkumar S, Phani KLN, Yegnaraman V (2008) Mater Lett 62:571–573
Terzi F, Zanardi C, Martina V, Pigani L, Seeber R (2008) J Electroanal Chem 619–620:75–82
Harish S, Mathyarasu J, Phani KLN (2008) J Appl Electrochem 38:1583–1588
Atta NF, El-Kady MF (2009) Talanta 79:639–647
Zen JM, Chung HH, Kumar AS (2002) Anal Chem 74:1202–1206
Ravi Shankaran D, Iimura K, Kato T (2003) Sens Actuators B 94:73–80
Stoyanova A, Tsakova V. J Solid State Electrochem accepted for publication
Winkels S, Tsakova V, Schultze JW (1998) Proc Electrochem Soc 98–26:97–104
Tsakova V, Winkels S, Schultze JW (2000) Electrochim Acta 46:759–76
Stromberg C, Tsakova V, Schultze JW (2003) J Electroanal Chem 547:125–133
Ilieva M, Tsakova V (2004) Synth Met 141:281–285
Ilieva M, Tsakova V (2004) Synth Met 141:287–292
Ilieva M, Tsakova V (2005) Electrochim Acta 50:1669–1674
Safavi A, Maleki N, Moradlou O, Tajabadi F (2006) Anal Biochem 359:224–229
Acknowledgments
Donation of EDOT by H.C. Strack GmbH, Germany is gratefully acknowledged. The investigations are completed with the financial support of Bulgarian Ministry for Education and Science obtained under contracts X-1405 and VUH 307/2007.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Stoyanova, A., Tsakova, V. Copper-modified poly(3,4-ethylenedioxythiophene) layers for selective determination of dopamine in the presence of ascorbic acid: I. Role of the polymer layer thickness. J Solid State Electrochem 14, 1947–1955 (2010). https://doi.org/10.1007/s10008-010-1007-y
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10008-010-1007-y