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The impact of lip-split mandibulotomy on patients treated for pT2 oral tongue squamous cell carcinoma: a study of 224 patients

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Abstract

Background

Head and neck surgeons often face a challenge in order to achieve adequate three-dimensional resection of tumours in the oral cavity, especially in the dentate patient.

Methods

We compared the outcomes of lip-split mandibulotomy and trans-oral access, respectively, in patients treated for primary pT2 oral tongue SCC with regard to the status of the resection margins and the incidence of tumour recurrence.

Results

Multivariate analysis showed a non-significant effect of the surgical technique used to the reported recurrence, F(1, 224) = 0.350, p = .555 and a significant effect on the margins achieved F(1, 224) = 11.381, p = .001.

Conclusions

Defects after excision of larger and more posterior tumours that are going to be reconstructed with free flaps represent a more probable indication for using an osteotomy access technique. Lip-split mandibulotomy is a low-morbidity technique which can deliver a sound oncological outcome and can be relatively easily taught to less experienced surgeons.

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Authors and Affiliations

  1. Dublin Dental University Hospital, 2 Lincoln Place, Dublin, D02 VX37, Ireland

    Panagiotis Stathopoulos

  2. Panteion University, Athens, Greece

    Maria Elli Doufexi Kaplani

  3. Swansea University, Swansea, UK

    Nikolaos Kostis

  4. Biostatistics, Heraklion General Hospital, Heraklion, Greece

    Dimosthenis Igoumenakis

  5. Northampton General Hospital, Northampton, UK

    William P. Smith

Authors
  1. Panagiotis Stathopoulos
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  2. Maria Elli Doufexi Kaplani
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  3. Nikolaos Kostis
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  4. Dimosthenis Igoumenakis
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  5. William P. Smith
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Corresponding author

Correspondence to Panagiotis Stathopoulos.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Stathopoulos, P., Kaplani, M.E.D., Kostis, N. et al. The impact of lip-split mandibulotomy on patients treated for pT2 oral tongue squamous cell carcinoma: a study of 224 patients. Oral Maxillofac Surg 25, 313–318 (2021). https://doi.org/10.1007/s10006-020-00918-8

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  • DOI: https://doi.org/10.1007/s10006-020-00918-8

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