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Evaluation of the impact of preoperative use of dexamethasone and cyclobenzaprine in surgical extraction of lower third molars on trismus by electromyographic analysis

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Abstract

Purpose

The aim of this study was to evaluate the influence of cyclobenzaprine and dexamethasone on ​the electrical activity of the masticatory muscles in patients who had undergone lower third molar surgery.

Methods

Thirty bilateral impacted lower third molars with indication of extraction were randomised into three groups: the control group, the dexamethasone, and the cyclobenzaprine group. To obtain muscular electrical activity and mouth opening, an electromyographic device was used at mandibular rest and maximum voluntary contraction and compared pre- and post-operatively.

Results

During muscle contraction, no significant difference was observed in the electromyographic records on the non-operated side. On the operated side, there was a reduction in electrical activity for both drugs pre-operatively and immediately post-operatively compared to the control group. All pharmacological agents promoted a higher mouth opening compared to control group.

Conclusion

The results suggest that dexamethasone and cyclobenzaprine may be useful as an adjuvant in the prevention of motor dysfunctions in third molar surgery.

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Authors and Affiliations

  1. Department of Surgery and Oral Diagnoses, College of Dentistry, State University of São Paulo – UNESP, São José dos Campos, Brazil

    Fernando Vagner Raldi, Rodrigo Dias Nascimento, Fábio Ricardo Loureiro Sato & Michelle Bianchi de Moraes

  2. Department of Oral and Maxillofacial Surgery, College of Dentistry, State University of São Paulo – UNESP, Av. Eng. Francisco José Longo, 777, São José dos Campos, SP, 12245-000, Brazil

    Fábio Ricardo Loureiro Sato

  3. Department of Bioscience and Oral Diagnoses, College of Dentistry, State University of São Paulo – UNESP, São José dos Campos, Brazil

    Lucio Murillo Santos & José Benedito Oliveira Amorim

Authors
  1. Fernando Vagner Raldi
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Correspondence to Fábio Ricardo Loureiro Sato.

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Raldi, F.V., Nascimento, R.D., Sato, F.R.L. et al. Evaluation of the impact of preoperative use of dexamethasone and cyclobenzaprine in surgical extraction of lower third molars on trismus by electromyographic analysis. Oral Maxillofac Surg 23, 395–405 (2019). https://doi.org/10.1007/s10006-019-00776-z

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