Abstract
The development of de novo sequencing tools has led to the massive production of genomes and transcriptomes from many unconventional animal models. To tackle this huge flow of data, PepTraq brings together many functionalities generally scattered in multiple tools, so that sequences can be filtered on the basis of multiple criteria. It is particularly suitable for the identification of non-annotated transcripts, re-annotation, extraction of secretomes, neuropeptidomes, targeted search for peptides and proteins, preparing specific proteomics/peptidomics fasta files for mass spectrometry (MS) applications, MS data processing, etc. PepTraq is developed in Java, and is available as a desktop application that can be downloaded from https://peptraq.greyc.fr. It is also available as a web application at the same URL for processing small files (10–20 MB). The source code is open under a CeCILL-B licence.
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Data sharing not applicable to this article as no datasets were generated or analysed during the current study.
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Funding
This work was partially supported by the région Basse-Normandie (France) as part of Projet Émergent n°16E00790/16P03508.
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BZ, JH, and CZ-G imagined the tool described in the article and its precise functionalities. BZ is the main developer of this tool. CC developed the online version, AO added functionalities to the desktop version, and VR supervised part of the development. All authors reviewed the manuscript.
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Zanuttini, B., Henry, J., Couronne, C. et al. PepTraq: a toolbox for in silico data mining and fast sequence filtering. Amino Acids 55, 709–712 (2023). https://doi.org/10.1007/s00726-023-03251-y
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DOI: https://doi.org/10.1007/s00726-023-03251-y