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Two-dimensional NMR relaxation study of the pore structure in silicone hydrogel contact lenses

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Abstract

A combination of two-dimensional nuclear magnetic resonance (NMR) proton relaxometry and differential interference contrast optical microscopy is used to compare the pore structures of hydroxyethyl methacrylate-based hydrogels used in conventional contact lenses with three silicone hydrogels primarily developed for continuous-wear contact lenses. It is shown that both types of hydrogel have a connected network of nanopores but that, in addition, the silicone hydrogels contain pores on the micrometer scale that enhances their permeability. The potential of other two-dimensional NMR relaxation and diffusion methods for detailed characterization of hydrogels is discussed.

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Authors and Affiliations

  1. Anglia Ruskin University, Cambridge, UK

    D. T. R. Austin

  2. Institute of Food Research, Norwich, UK

    B. P. Hills

  3. Institute of Food Research, Norwich Research Park, Colney, Norwich, NR47UA, UK

    B. P. Hills

Authors
  1. D. T. R. Austin
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  2. B. P. Hills
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Correspondence to B. P. Hills.

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Austin, D.T.R., Hills, B.P. Two-dimensional NMR relaxation study of the pore structure in silicone hydrogel contact lenses. Appl Magn Reson 35, 581–591 (2009). https://doi.org/10.1007/s00723-009-0187-z

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  • DOI: https://doi.org/10.1007/s00723-009-0187-z

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