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Characterization of narcotics using differential mobility spectrometry

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Abstract

The topic of this work is the use of differential mobility spectrometry for the characterization of narcotics. Studies were performed for amphetamine, methamphetamine, ketamine, heroin, and cocaine dissolved in methanol. Each target molecule appears at a specific compensation voltage under a fixed value of radiofrequency (RF) voltage. Values of compensation voltage of product ion peak at RF = 1480 V for cocaine, heroin, ketamine, methamphetamine, and amphetamine at 110 °C appears at 3.33, 2.43, 2.12, −0.56, and −4.9 V, respectively. Nonlinear function curves were used for graphical differentiation of measured narcotics. This study also deals with the effects of temperature on peak position in differential mobility spectra. This rapidly developed method allows characterization of five illicit drugs in 100 s.

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Acknowledgements

This study was financially supported by the Research plan No. VG20132015107 “DRAGON—The Hand-held Narcotic Compounds Sniffer & Analyzer (2013–2015, MV0/VG)”, which was financed by the Ministry of the Interior of the Czech Republic (Security Research for the Needs of the State 2010–2015).

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Authors and Affiliations

  1. Department of Analytical Chemistry, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 532 10, Pardubice, Czech Republic

    Martin Pavlačka, Karel Ventura & Petra Bajerová

  2. RS DYNAMICS s.r.o., Starochodovská 1359/86, 14900, Prague 4, Czech Republic

    Kateřina Kortánková, Jiří Bláha, Michal Zástěra & Roman Mázl

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  1. Martin Pavlačka
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  2. Karel Ventura
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  3. Kateřina Kortánková
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  4. Jiří Bláha
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  5. Michal Zástěra
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  6. Roman Mázl
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  7. Petra Bajerová
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Correspondence to Petra Bajerová.

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Pavlačka, M., Ventura, K., Kortánková, K. et al. Characterization of narcotics using differential mobility spectrometry. Monatsh Chem 148, 1599–1604 (2017). https://doi.org/10.1007/s00706-017-1923-y

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  • DOI: https://doi.org/10.1007/s00706-017-1923-y

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