Summary.
The canine herpesvirus infected cell protein 0 (CICP0) gene was sequenced. The CICP0 gene was transcribed as a 1.4 kb mRNA from the end of the unique long region nearby the internal repeat during early phase of productive infection of the virus. An open reading frame of the gene encodes a polypeptide of 333 amino acids. The RING finger domain and acidic transcriptional activation domain were found at the N-terminus and within the middle region in the deduced amino acid sequence, respectively, suggesting that the CICP0, like the ICP0 of herpes simplex virus 1, is a transactivating protein.
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Received September 6, 1999 Accepted March 9, 2000
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Miyoshi, M., Takiguchi, M., Yasuda, J. et al. Structure of the infected cell protein 0 gene of canine herpesvirus. Arch. Virol. 145, 1715–1723 (2000). https://doi.org/10.1007/s007050070086
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DOI: https://doi.org/10.1007/s007050070086