Skip to main content
SpringerLink
Log in

Coding-complete sequencing classifies parrot bornavirus 5 into a novel virus species

  • Original Article
  • Published:
Archives of Virology Aims and scope Submit manuscript

Abstract

In this study, we determined the sequence of the coding region of an avian bornavirus detected in a blue-and-yellow macaw (Ara ararauna) with pathological/histopathological changes characteristic of proventricular dilatation disease. The genomic organization of the macaw bornavirus is similar to that of other bornaviruses, and its nucleotide sequence is nearly identical to the available partial parrot bornavirus 5 (PaBV-5) sequences. Phylogenetic analysis showed that these strains formed a monophyletic group distinct from other mammalian and avian bornaviruses and in calculations performed with matrix protein coding sequences, the PaBV-5 and PaBV-6 genotypes formed a common cluster, suggesting that according to the recently accepted classification system for bornaviruses, these two genotypes may belong to a new species, provisionally named Psittaciform 2 bornavirus.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Adams MJ, Lefkowitz EJ, King AMQ, Bamford DH, Breitbart M, Davison AJ, Ghabrial SA, Gorbalenya AE, Knowles NJ, Krell P, Lavigne R, Prangishvili D, Sanfaçon H, Siddell SG, Simmonds P, Carstens EB (2015) Ratification vote on taxonomic proposals to the International Committee on Taxonomy of Viruses (2015). Arch Virol 160:1837–1850. doi:10.1007/s00705-015-2425-z

  2. Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ (1990) Basic local alignment search tool. J Mol Biol 215:403–410

    Article  CAS  PubMed  Google Scholar 

  3. Cubitt B, Oldstone C, de la Torre JC (1994) Sequence and genome organization of borna disease virus. J Virol 68:1382–1396

    PubMed Central  CAS  PubMed  Google Scholar 

  4. Honda T, Tomonaga K (2013) Nucleocytoplasmic shuttling of viral proteins in borna disease virus infection. Viruses 5:1978–1990. doi:10.3390/v5081978

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  5. Honkavuori KS, Shivaprasad HL, Williams BL, Quan PL, Hornig M, Street C, Palacios G, Hutchison SK, Franca M, Egholm M, Briese T, Lipkin WI (2008) Novel borna virus in psittacine birds with proventricular dilatation disease. Emerg Infect Dis 14:1883–1886. doi:10.3201/eid1412.080984

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  6. Horie M, Ueda K, Ueda A, Honda T, Tomonaga K (2012) Detection of avian bornavirus 5 RNA in Eclectus roratus with feather picking disorder. Microbiol Immunol 56:346–349. doi:10.1111/j.1348-0421.2012.00436.x

    Article  CAS  PubMed  Google Scholar 

  7. Kistler AL, Gancz A, Clubb S, Skewes-Cox P, Fischer K, Sorber K, Chiu CY, Lublin A, Mechani S, Farnoushi Y, Greninger A, Wen CC, Karlene SB, Ganem D, DeRisi JL (2008) Recovery of divergent avian bornaviruses from cases of proventricular dilatation disease: identification of a candidate etiologic agent. Virol J 5:88. doi:10.1186/1743-422X-5-88

    Article  PubMed Central  PubMed  Google Scholar 

  8. Kobayashi T, Kamitani W, Zhang G, Watanabe M, Tomonaga K, Ikuta K (2001) Borna disease virus nucleoprotein requires BOTH nuclear localization and export activities for viral nucleocytoplasmic shuttling. J Virol 75:3404–3412. doi:10.1128/JVI.75.7.3404-3412.2001

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  9. Kuhn JH, Dürrwald R, Bào Y, Briese T, Carbone K, Clawson AN, deRisi JL, Garten W, Jahrling PB, Kolodziejek J, Rubbenstroth D, Schwemmle M, Stenglein M, Tomonaga K, Weissenböck H, Nowotny N (2015) Taxonomic reorganization of the family Bornaviridae. Arch Virol 160:621–632. doi:10.1007/s00705-014-2276-z

    Article  CAS  PubMed  Google Scholar 

  10. Ladner JT, Beitzel B, Chain PS, Davenport MG, Donaldson EF, Frieman M, Kugelman JR, Kuhn JH, O’Rear J, Sabeti PC, Wentworth DE, Wiley MR, Yu GY, Sozhamannan S, Bradburne C, Palacios G, Threat Characterization Consortium (2014) Standards for sequencing viral genomes in the era of high-throughput sequencing. MBio 5:e01360-14. doi:10.1128/mBio.01360-14

    Article  PubMed Central  PubMed  Google Scholar 

  11. Mihalov-Kovács E, Fehér E, Martella V, Bányai K, Farkas SL (2014) The fecal virome of domesticated animals. Virusdisease 25:150–157. doi:10.1007/s13337-014-0192-1

    Article  PubMed Central  PubMed  Google Scholar 

  12. Nicholas KB, Nicholas HB Jr, Deerfield DW II (1997) GeneDoc: analysis and visualization of genetic variation. Embnet News 4:14

    Google Scholar 

  13. Philadelpho NA, Rubbenstroth D, Guimarães MB, Piantino Ferreira AJ (2014) Survey of bornaviruses in pet psittacines in Brazil reveals a novel parrot bornavirus. Vet Microbiol 174:584–590. doi:10.1016/j.vetmic.2014.10.020

    Article  PubMed  Google Scholar 

  14. Schwemmle M, Carbone KM, Tomonago K, Nowotny N, Garten W (2011) Family Bornaviridae. In: King AMQ, Adams MJ, Carstens EB, Lefkowitz EJ (eds) Virus taxonomy: classification and nomenclature of viruses. Ninth report of the international committee on taxonomy of viruses. Elselvier, San Diego, pp 658–664

    Google Scholar 

  15. Stenglein MD, Leavitt EB, Abramovitch MA, McGuire JA, DeRisi JL (2014) Genome sequence of a bornavirus recovered from an African Garter Snake (Elapsoidea loveridgei). Genome Announc 2(5):e00779-14. doi:10.1128/genomeA.00779-14

    Article  PubMed Central  PubMed  Google Scholar 

  16. Tamura K, Stecher G, Peterson D, Filipski A, Kumar S (2013) MEGA6: molecular evolutionary genetics analysis version 6.0. Mol Biol Evol 30:2725–2729

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  17. Tomonaga K, Kobayashi T, Ikuta K (2002) Molecular and cellular biology of borna disease virus infection. Microbes Infect 4:491–500

    Article  CAS  PubMed  Google Scholar 

  18. Weissenböck H, Bakonyi T, Sekulin K, Ehrensperger F, Doneley RJT, Dürrwald R, Hoop R, Erdélyi K, Gál J, Kolodziejek J, Nowotny N (2009) Avian bornaviruses in psittacine birds from Europe and Australia with proventricular dilatation disease. Emerg Infect Dis 15:1453–1459. doi:10.3201/eid1509.090353

    Article  PubMed Central  PubMed  Google Scholar 

Download references

Acknowledgments

Our work was supported by the Momentum Program of the Hungarian Academy of Sciences.

Author information

Authors and Affiliations

  1. Centre for Agricultural Research, Institute for Veterinary Medical Research, Hungarian Academy of Sciences, Hungária krt. 21, 1581, Budapest, Hungary

    Szilvia Marton, Krisztián Bányai, Katalin Ihász, Renáta Kugler & Szilvia L. Farkas

  2. Department of Exotic Animal and Wildlife Medicine, Faculty of Veterinary Science, Szent István University, István u. 2, 1078, Budapest, Hungary

    János Gál

  3. Medical Centre of Hungarian Defense Forces, Force Health Laboratory Institute, Róbert Károly krt. 44, 1134, Budapest, Hungary

    György Lengyel

  4. János Szentágothai Research Centre, University of Pécs, Ifjúság útja 20, 7624, Pecs, Hungary

    Ferenc Jakab

  5. Department of Microbiology and Infectious Diseases, Faculty of Veterinary Science, Szent István University, Hungária krt. 23-25, 1143, Budapest, Hungary

    Tamás Bakonyi

Authors
  1. Szilvia Marton
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Krisztián Bányai
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. János Gál
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Katalin Ihász
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Renáta Kugler
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. György Lengyel
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Ferenc Jakab
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Tamás Bakonyi
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Szilvia L. Farkas
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Szilvia L. Farkas.

Electronic supplementary material

Below is the link to the electronic supplementary material.

Supplementary material 1 (PPTX 66 kb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Marton, S., Bányai, K., Gál, J. et al. Coding-complete sequencing classifies parrot bornavirus 5 into a novel virus species. Arch Virol 160, 2763–2768 (2015). https://doi.org/10.1007/s00705-015-2546-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00705-015-2546-4

Keywords

Search

Navigation